ObjectiveTo explore effectiveness and rationality of using concept of enhanced recovery after surgery in treatment of hepatic hemangioma. MethodsThe clinical data of 289 patients with hepatic hemangioma underwent hepatectomy were analyzed retrospectively.These patients were divided into enhanced recovery after surgery group (n=146) and traditional perioperative treatment group (n=143) according to the different perioperative treatment methods.The postoperative hospital stay,hospitalization cost,postoperative bilirubin levels on day 1,3,and 5,postoperative complications rate,postoperative 24 h and 48 h pain numeric rating scale (NRS) score,postoperative ambulation status,intestinal ventilation time,mortality,and readmission rate were compared between these two groups. ResultsCompared with the traditional perioperative treatment group,the postoperative hospital stay and intestinal ventilation time were shorter (P<0.05),hospitalization cost was less (P<0.05),postoperative complications rate was lower (P<0.05),points of postoperative 24 h and 48 h NRS were lower (P<0.05),proportion of postoperative ambulation on day 1 was higher (P<0.05) in the enhanced recovery after surgery group.While the differences of the postoperative bilirubin levels on day 1,3,and 5,mortality,and readmission rate were not significantly different between these two groups (P>0.05). ConclusionThe concept of enhanced recovery after surgery in treatment of hepatic hemangioma is feasible and safe,which is in favor of postoperative functional recovery,and could shorten postoperative hospital stay and reduce hospitalization cost.