【摘要】 目的 探讨64层螺旋CT尿路造影在上尿路梗阻性病变中的运用及诊断价值。 方法 收集2009年12月—2011年1月132例行螺旋CT尿路造影，并确诊为上尿路梗阻病变患者资料，分析其图像特点并与手术及病理结果对比。 结果 132例患者经临床及手术病理证实，输尿管结石31例，先天异常及畸形51例，输尿管感染性病变16例，尿路肿瘤29例，外源性压迫3例，肾盂旁囊肿2例；所有患者均显示良好，与临床及病理结果基本吻合。 结论 CT尿路造影能多方位清楚显示病变内部及周围情况，可准确的显示、判断尿路梗阻的原因、性质，是一种对泌尿系疾病诊断极有价值的影像学检查方法。【Abstract】 Objective To discuss the utilization and diagnostic value of 64-slice spiral CT urography for upper urinary tract obstruction diseases. Methods We collected the clinical data of 132 patients who were diagnosed with upper urinary tract obstruction by 64-slice spiral CT urography between December 2009 and January 2011. We analyzed the imaging features and compared them with surgical and pathological results. Results Confirmed by surgical and pathological results, 132 patients included 31 cases of urethral stone, 51 cases of congenital variant and malformation, 16 cases of ureteral infection, 29 cases of tumors in urinary tract, 3 cases of extraneous compression, and 2 cases of cysts next to the renal pelvis. CT diagnosis for all cases were basically in line with clinical and pathological results. Conclusion CT urography is an extremely valuable imaging method to diagnose the diseases of urinary system. It can display lesions broadly and reveal their inner and peripheral circumstances clearly, thus can help us determine the reasons and natures of the lesions precisely.