ObjectiveTo investigate the effect of changing of body posture on video-assisted thoracoscopic surgery for pulmonary bullae. MethodsFrom January 2011 to October 2012, 28 patients with pulmonary bullae including 21 males and 7 females were admitted to our department. The median age of these patients was 18 years old, ranging from 16 to 61. All patients were divided into two groups:video-assisted pulmonary bullae resection with changing of body posture (n=14) and without changing of body posture (n=14). Surgery time, blood loss during operation, drainage, duration of drainage, length of stay in hospital, incidence of complications and recurrence rate were observed and compared between the two groups. ResultsSurgery time in the non-change group was shorter than that in the change group (P<0.05). Blood loss during operation in the non-change group was less than that in the change group (P<0.05). There were no significant difference in drainage, duration of drainage, length of stay in hospital and recurrence rate between the two groups (P>0.05). No complications occurred. ConclusionFor patients with bilateral bullae having tolerated cardiopulmonary function and not-heavy pleural adhesions, non-changing of body posture is safe and effective, not only to avoid a second surgery, but also to avoid turning over and second surgical disinfection, which is more beneficial to the patients.