ObjectiveTo explore the knowledge and attitude of pain management in undergraduate nursing students, analyze the influencing factors, and improve the future education of the undergraduate nursing students. MethodsA total of 220 undergraduate nursing students were investigated with the Knowledge and Attitudes Survey Regarding Pain between November 2014 to June 2013. ResultsUndergraduate nursing students were lack of cognition on pain management and attitude, with an average wrong answer rate of 55.70%; the difference in reading related books or journals in pain, pain management training, and frequency of usage of pain assessment tools among the influential factors were significant (P < 0.05). The most common factor was the lack of pain management training. ConclusionsThe knowledge level of pain management in undergraduate nursing students who are lack of pain management training needs to be improved. Medical schools might optimize pain management courses, and hospitals should enhance the pain management training of clinical nurses so as to make them assess patients correctly by using pain assessment tools. In addition, it's necessary to enhance the nursing students' pain management practice during the clinical practice, so as to improve the pain management knowledge level in undergraduate nursing students.