Fiftyone thumbs with complete or partial loss of the distal segment in 50 patients has been reconstructed with transplantation of great or second toe by microsurgical technique from 1985 to 1993. All cases were survived and regained favourable functions. Ninteen cases had been followup after operation, with an average of 51 months. In the group Ⅱ° of thumb loss, the overall functional impairment inproved from 11% to 1.7%, and in the remaining cases, from 5% to 0%. Sensation examination found S+3 in 42%, S4 in 37% and the two point discrimination between 4mm to 10mm. The merits of reconstruction of the distal thumb segment was stated and emphasized. The choice of operative procedures, the advantagesof emergency reconstruction, the selection emphasized of anastomosis site of blood vessels and the complications and sequelae of the donor foot were discussed in detaill.