ObjectiveTo determine the diagnosis method for an elderly male patient with hematuria by means of evidence-based practice, so as to provide references for clinical diagnosis. MethodWe searched databases including PubMed, EMbase, and The Cochrane Library up to Nov. 2014, to collect relevant diagnostic evidence for elderly patients with hematuria. ResultsCompared with MRI, CT had higher sensitivity and specificity in determination of lesion location in where the hematuria was caused by tumor. ConclusionsCT scan may be better for patients with hematuria to determine the location of lesion.