Objective To study the effectiveness, safety and tolerance of testosterone undecanoate （TU） in improving exhaustion and quality of life （QOL） of the elderly male patients with chronic disease in advanced stage. Methods Using a simple randomized controlled trial design, eighty patients were randomized into two groups. The treatment group took routine therapy and TU and the control group with routine therapy alone. Results 1. Baseline characteristics in both groups were similar. 2. The PADAM grade decreased, and the QOL scale increased in the treatment group （P〈0.05 ）. 3. Serum total testosterone in the treatment group rose, upper arm circumference and right hand grip improved （P〈0.05 ）. 4. There were no significant differences in adverse effects between both groups. Conclusions TU can improve the clinical health status in the elderly male patients with chronic disease in advanced stage and increase serum testosterone level, there is a satisfactory tolerances and few adverse reactions.
ObjectiveTo investigate the optimal catheter extubation time by comparing the postoperative complications in elderly patients undergoing total hip arthroplasty with catheter extubation at different times. MethodsBetween May and August 2013, 60 patients needing total hip replacement were randomly divided into experimental group and control group with 30 in each. The patients' average age of the experimental group was 75.6 years (65-87 years) and of the control group was 76.9 years (66-85 years). Extubation was performed within 24 hours after surgery in the experimental group, while it was performed after 24 hours after surgery in the control group. All the patients underwent clean catheterization with a Foley catheter two hours before surgery. The catheter indwelling time, first time of self-urination, urination after extubation, and complications were recorded and compared between the two groups carefully. ResultsThe incidence of complications (urinary retention, urethral pain, cystospasm and urinary irritant symptoms) in the experimental group was significantly less than the control group (P<0.05). The first urination time had no significant difference (P>0.05) between the two groups. ConclusionThe extraction of indwelling catheter in the early postoperative period (within 24 hours) can reduce the incidence of complications and is better for the early postoperative rehabilitation.