Objective To retrospectively analyze the characteristics and death causes among the Wenchuan earthquake victims in The Third People’s Hospital of Chengdu so as to provide information for reducing mortality in future earthquake disasters. Methods The analysis was based on the data provided by the Department of Information, the Medical Record Library, and the Emergency Room of the hospital through July 12. Microsoft EXCEL was used for data input and SPSS 13.0 was used for statistical analyses. Results Through July 12, 9 (1.57%) out of the 575 wounded patients died, comprising 3 males and 6 females. Of those, 5 died in the outpatient department. The death causes were all related to severe cerebral injuries. The other 4 died in the inpatient department and the death causes were related to severe underlying illnesses and infection. Conclusion Screening and early treatment for cerebral injuries is very important in the period directly following the earthquake. Later, more attention should be paid to the treatment of underlying illnesses as well as the prevention and control of infection.
ObjectiveTo systematically review the associations of maternal diabetes mellitus with cleft lip and palate in offspring. MethodsThe PubMed, EMbase, Cochrane Library, Web of Science, CNKI, VIP and WanFang Data databases were electronically searched to collect the observational studies on the association of maternal diabetes mellitus with cleft lip and palate in offspring from inception to June, 2024. Two reviewers independently screened literature, extracted data and assessed the risk of bias of the included studies. Meta-analysis was then performed by using Stata 17.0 and RevMan 5.4 software. ResultsA total of 34 studies involving 2 556 911 participants were included. The results of meta-analysis showed that maternal pregestational diabetes mellitus was associated with an increased risk of cleft lip and palate in offspring (OR=1.91, 95%CI 1.59 to 2.30, P<0.01). Maternal type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) were also associated with an increased risk of cleft lip and palate in offspring(T1DM: OR=2.28, 95%CI 1.65 to 2.30, P<0.01; T2DM: OR=1.87, 95%CI 1.10 to 3.19, P<0.01). There was no correlation between maternal gestational diabetes mellitus and cleft lip and palate in offspring. ConclusionCurrent evidence shows that maternal pregestational diabetes mellitus was associated with an increased incidence of cleft lip and palate in offspring. Due to the limited quality and quantity of the included studies, more high quality studies are needed to verify the above conclusion.