Objective To analyze the current state, evaluate the accuracy, and determine the influencing factors of diabetes-related subscriptions on the WeChat platform. Methods The top 100 WeChat platforms on the "China WeChat Platform New Rank Annual List 2020" were searched using the term "diabetes". We identified diabetes-related subscriptions published from June 1, 2021 to August 31, 2021. The accuracy of subscriptions was analyzed according to the consistency with clinical practice guidelines, and was independently assessed by two specialists. SPSS 22.0 software was used for data analysis. Results Sixty-eight subscriptions from 26 WeChat platforms were included. Twenty-five (36.8%) subscriptions were evaluated as inconsistent. The numbers of "wow" per thousand reads and "like" per thousand reads of inconsistent diabetic subscriptions were statistically higher than those of consistent diabetic subscriptions (P<0.05). Subscriptions with expert support (80.8% vs. 52.4%) and evidence support (91.7% vs. 57.1%) shared a higher consistency (P<0.05). Subscriptions with commercial promotion (16.7% vs. 67.7%) had a lower consistency (P=0.02). Conclusion Although some content is inconsistent with guidelines, diabetes-related subscriptions have a certain dissemination ability on the WeChat platform. Moreover, readers are more likely to "wow" or "like" for inconsistent subscriptions. Diabetes-related subscriptions on the WeChat public platform need supervision and can be further regulated by providing evidence support and regulating commercial promotion.