ObjectiveTo investigate the prevalence and risk factors of hypertension in urban and rural residents in Chengdu. MethodsA cluster random sampling survey was carried out from February to October in 2010. A total of 2 011 residents aged 35-70 years in four communities of Chengdu (two communities in urban area, two in rural area) were investigated for the incidence of hypertension. Analysis was performed using SPSS 18.0 software. ResultsThe standardized prevalence of hypertension was 31.30% among residents aged 35-70 years, which was much higher in urban than that in rural:39.03% vs. 24.90% (P < 0.05). The results of multivariate logistic regression analysis showed that, age, waist, heart rate, fasting blood glucose and education level were the major risk factors of hypertension for male; while age, waist, heart rate, fasting blood glucose, triglyceride and uric acid were the major risk factors for female. ConclusionThe prevalence of hypertension in urban is higher than that in rural in Chengdu. Prevention and intervention should be performed more for whom have increased waist circumfluence, abnormal levels of fasting glucose, and increased heart rate.