【摘要】 目的 探讨医院产前超声检查中应用知情同意书的价值。 方法 对2002年1月-2010年1月经产前超声常规筛查并分娩出生缺陷儿（均为基层医院常规超声筛查难以显示或无法诊断的先天性异常）的产妇，按实行知情同意前后分为两组：实施前的有21例（A组），实施后的有19例（B组），比较两组出生缺陷儿产妇对产后结果的反映情况。 结果 B组产妇对产前超声筛查理解13例，可以理解4例，难以理解2例；A组理解3例，可以理解5例，难以理解13例，两组理解程度差异有统计学意义（Z=-3.741，P=0.000）。 结论 知情同意书是产前超声检查过程中孕妇对医方理解及对孕妇负责的必要手段。 【Abstract】 Objective To explore the value of informed consent in prenatal ultrasonographic examination. Methods Between January 2002 and January 2010, the puerperants who underwent routine screening by prenatal ultrasonography in our hospital and delivered the birth of babies with defects (conventional ultrasound screening in basic-level hospitals hard to display or unable to diagnosis of congenital anomaly) were selected. The patients were divided into two groups according to whether had informed consent. The responses after the parturition (having babies with defects) of the puerperants between the two groups were compared. Results The puerperants in informed consent group had more objective understanding of prenatal ultrasonographic examination, and better acceptance level of the results of ultrasonography. Conclusion Informed consent of prenatal ultrasonography process is necessary.