ObjectiveTo investigate the anxiety of family members of patients with Parkinson's disease, and explore the risk factors. MethodsSelf-rating Anxiety Scale (SAS) was employed to assess a total of 107 family members of Parkinson disease patients from October 2014 to October 2015. The scores were compared with the domestic norm, and the risk factors of anxiety were analyzed with Logistic regression. ResultsThe scores of SAS (38.83±10.97) were significantly higher in patients' family members than the norm (P<0.01). Disturbance of the life and work by caring the patients, late stage of the patients, and disability of self care were independent risk factors for the anxiety of the patients' family members (P<0.01), and the three factors could increase the anxiety (OR>1). ConclusionAnxietsy exists in family members of patients with Parkinson disease. More attention should be paid when they have the factors of disturbance of the life or work by caring the patients, late stage of the patients, and self care disability of patients.