The model of acut hemorrhagic necrotizing pancreatitis(AHNP)was produced by retrograde injection of 3% sodium taurocholate into the biliopancreatic duct.48rats with AHNP were treated with Tanshin by subcutaneous injection(100mg/100g body weight,q12h,tanshin group),48 rats with AHNP without any treatment as control(control group).The resule showed that in the control group,there were severe hemorrhage,necroses and the lesions of microvascular,the activity of pancreatic enzyme in serum increased significantly(Plt;0.01)at 6h,after 12h the activities of those pancreatic enzymes decreased gradually, the lesions of microvascular and histology were becoming severer.In the Tanshin group,at 24h the lesions of microvascular and histology of the pancreas were modified significantly (Plt;0.05).These results suggest that the lesion of microcirculation play an important role in the later AHNP,and Tanshin has some effects on the AHNP by modifying the microcirculation of the pancreas.
This paper reports twelve patients underwent repeat hepatic resection because of the recurrence of hepatocellular carcinomas after primary resection. The indication of reoperation, selection of incision, difficults encountered in the operation and the treatment after operation are discussed. The authors believe that the second operation is technically more difficult than the first one, some troubles my be happened during the operation and put forward some ways to deal with this situations.