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find Author "HU Shanlian" 5 results
  • The Introduction to Research Methods on Evidence-Informed Policy Making

    Evidence-informed decision making is one of the most common, objective and important health policy research methods used by policy makers. Its purpose is to promote the application and dissemination of research knowledge on health policy and systems to change traditional and subjective models of health policy making in order to improve national and regional health systems. Three elements will influence the effectiveness of health policy making:research evidence, available health resources and the value of policy formulation. This paper introduces some pragmatic evidence-based approaches, especially systematic reviews, priority setting and a combined approach matrix (CAM). Systematic reviews have a b impact on the decision process for policy makers. We hope that the application and development of evidence-informed methods will increase in China’s health policy research.

    Release date:2016-09-07 02:15 Export PDF Favorites Scan
  • Economic Evaluation of Pharmaceuticals after Marketing Approval

    This paper discusses the characteristics of pharmacoecomomics and its evaluation methods. After launching a drug to the market, a large amount of clinical use provides the opportunity to evaluate the effectiveness and adverse effects. The methods of economic evaluation in post-marketing pay more attention to the value-added pharmacoeconomics activities to maintain product status, such as risk-benefit analysis, drug reimbursement application and budget impact analysis, etc.

    Release date:2016-09-07 02:25 Export PDF Favorites Scan
  • Systematic Review of Economic Analyses: Methods and Challenges

    Based on the principles and methods of systematic review of randomized controlled clinical trials, systematic review of economic analyses can integrate information from multiple economic studies which focus on the same clinical questions. It can also provide important insights by systematically examining how differences among studies lead to different results. Generally, there are seven steps to conduct such a review: 1) formulating questions; 2) establishing eligibility criteria; 3) searching and selecting eligible economic analyses; 4) assessing the validity of economic analyses; 5) acquiring data; 6) analyzing and synthesizing data; and 7) presenting results. Owing to the specificity of economic analyses, many methodological challenges exist, including the varieties of economic models, analytic perspectives, time horizons, and uncertainty and sensitivity analysis among different economic analyses. This may cause difficulties for critical assessment of the economic analyses.

    Release date:2016-09-07 02:11 Export PDF Favorites Scan
  • Cost Analysis in Clinical Trials

    Economic evaluation used alongside clinical trials has become a hot spot in the development of clinical studies. The definition and classification of the cost were introduced in this article. The ways to conduct cost analysis in clinical trials were introduced systematically, including the identification, collection and analysis of the data of costs, and the concern of the analysis.

    Release date:2016-09-07 02:27 Export PDF Favorites Scan
  • Research on techniques of economic evaluations of drugs by using the real-world data

    The application of economic tools to evaluate the cost and health benefits and screen out more cost-effective drugs and technologies is an important measure to improve efficiency of medical resource allocation in China. Given the inherent differences between strict clinical trials and clinical routine practice, using trial-based economic evaluations to guide relevant medical decisions may lead to a certain risk of value deviation. Recent development of real-world data provides opportunities to assess the cost-effectiveness of drugs under the practical utilization, and has gradually become a new research hotspot. However, the complexity of the actual clinical environment also puts higher demands on researchers and decision makers to construct, understand and apply real-world evidence. In order to further prompt the normalization of economic evaluation based on real-world data and promote the scientific application of real-world evidence in medical and health decision-making, this project aims at the crucial issues including scope, research design and quality evaluation, to clarify the key considerations on the using of real-world evidence in medical decision-making. Combined with the international guidelines, the latest advancement of relevant research areas and the advice and opinions from multidisciplinary experts, we aim to provide technical references and guidance for researchers and decision makers, and to strengthen the evidence base of management policies.

    Release date:2024-05-13 09:35 Export PDF Favorites Scan
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