目的 探讨高龄初产妇临产前的心理状态，了解其负性心理原因，及时给予护理干预，使其顺利渡过围生期。 方法 2010年6月－2011年9月，将在待产且年龄≥35岁的60例初产妇归为高龄组，随机选取同期住院的适龄初产妇60例作为对照组，应用焦虑自评量表（SAS）、抑郁自评量表（SDS）及症状自评量表（SCL-90），对高龄初产妇进行产前心理评估及检测血中肾上腺素（E）和去甲肾上腺素（NE）水平。 结果 高龄初产妇产前的SAS和SDS评分及E和NE水平，SCL-90量表中总分及躯体化、强迫、焦虑、抑郁因子分与适龄组比较，差异有统计学意义（P＜0.01）；SAS评分与E、NE水平，SDS评分与E、NE水平均呈正相关，相关系数分别为：0.378、0.402、0.384、0.369（P＜0.01）。 结论 高龄初产妇分娩前多数存在不同程度的负性心理，应根据其不同情况给予相应的心理干预以促进产妇顺利渡过围生期。
Objective To analysis and explore the value of metagenomics next-generation sequencing (mNGS) and clinical characteristics of Chlamydia psittaci (C. psittaci) pneumonia. Methods Totally 5 patients who were diagnosed with C. psittaci pneumonia and were treated in the Department of Respiratory and Critical Care Medicine and the Department of Infectious Diseases of Huazhong University of Science and Technology Union Shenzhen Hospital from Febuary 2021 to March 2021 were enrolled in the study. The clinical data of the patients were analyzed, and the clinical characteristics of the disease and treatment experience were summarized. Results The main symptoms of the 5 patients were high fever and cough, 4 of them had a history of raising parrots. The white blood cell and the neutrophils were mostly normal or slightly increased, the C reactive protein and erythrocyte sedimentation rate were significantly increased. The chest CT showed exudation and consolidation of one or several lung lobes. The serious patients might develop respiratory failure, if they were not treated by effective antibiotics. The diagnosis was based on clinical manifestations, contact history and alveolar lavage fluid that were detected by mNGS technology of C. psittaci nucleic acid sequence. The accuracy of detecting pathogens in alveolar lavage fluid by mNGS was high. In addition, mNGS could also identify other bacteria or viruses. After the timely adjustment of treatment, the condition of the patients was improved relied on tetracycline drugs or quinolone drugs, which shortened the diagnosis time and course of C. psittaci pneumnonia and reduced the use of unnecessary antibacterial drugs. Conclusions mNGS is of great significance in diagnosing C. psittaci pneumonia. The timely use of appropriate antibacterial drugs can achieve favorable therapeutic effect.