west china medical publishers
Keyword
  • Title
  • Author
  • Keyword
  • Abstract
Advance search
Advance search

Search

find Keyword "Hematopoietic stem cell,Niche,Osteoblastic cell" 1 results
  • Mutual Regulation of Hematopoietic Stem Cell Niche

    【Abstract】Objective To give a summary of the current researches on hematopoietic stem cell niche. Methods Through extensive reviewing the related domestic and abroad literatures, the present summary reviews the components of hematopoietic stem cell niche, related cell factors and related cell signaling pathway participating in regulation of hematopoietic stem cell. Results The activities of hematopoietic stem cells are regulated by the niche (microenvironment), which is composed of hematopoietic stem cell and its surrounding cells. The regulation cannot be completed through one signaling pathway. Also, the self-renewal and differentiation of hematopoietic stem cell cannot be completed only through osteoblastic cells. Conclusion The niche regulates hematopoietic stem cells by different ways. With study in-depth, we will comprehensively understand the nature of stem cells and the study will provide a broader space to stem cell-based therapy.

    Release date:2016-09-08 11:43 Export PDF Favorites Scan
1 pages Previous 1 Next

Format

Content