west china medical publishers
Keyword
  • Title
  • Author
  • Keyword
  • Abstract
Advance search
Advance search

Search

find Keyword "Hypoxia-inducible factor 1, alpha subunit/physiology" 1 results
  • The expression of hypoxia inducible factor -1αin embryonic and postnatal rats′retinae

    Objective To investigate the expression of hypoxia inducible factor 1(HIF1alpha;) in ratsprime; retinae during the embryonic and earlier postnatal period. Methods The retinal expression patterns of HIF-1alpha; protein and mRNA of embryonic day 12 (E12), E16, E20, and postnatal day 1(P1) and P5 rats were determined by immunohistochemical staining and reverse transcriptionpolymerase chain reaction (RT-PCR). Results HIF-1alpha; protein was detected in the neural epithelial layer and the pigment epithelial layer at all those 5 timepoints, with higher expression in the ganglion cell layer and the inner plexiform layer, and seems limited to the ganglion cell layer when re tina became more mature. Embryonic rat retina had higher expression of HIF-1alpha; protein and mRNA than postnatal retina, the difference was significant (P<0.01). Conclusion The expression of HIF1alpha; in ratsprime;retina e differs from embryonic to earlier postnatal stages. 

    Release date:2016-09-02 05:42 Export PDF Favorites Scan
1 pages Previous 1 Next

Format

Content