west china medical publishers
Keyword
  • Title
  • Author
  • Keyword
  • Abstract
Advance search
Advance search

Search

find Keyword "Iron system gene" 1 results
  • Analysis of iron acquisition and transportation system in clinical Klebsiella pneumoniae isolates

    ObjectiveTo evaluate the relationship between the genes involved in regulating iron uptake and maintaining iron homeostasis in Klebsiella pneumoniae from different sources and pathogenicity.MethodsThe genomic DNA sequences of two strains of Klebsiella pneumoniae from different sources were sequenced, stitched together, annotated and analyzed by second generation sequencing technique. The transversal comparison between different types of Klebsiella pneumoniae in NCBI database of iron carrier gene cluster iroB/C/D.ResultsIn these two Klebsiella pneumoniae clinical strains, the strain isolated from liver abscess patient carried 11 different iron acquisition and transportation system specific genes, which were not found in the non-liver abscess patient strain. Combined with the analysis of this sequence, in the NCBI database, six different strains of Klebsiella pneumoniae showed iroB/C/D triple positive.ConclusionIron acquisition and transportation system in Klebsiella pneumoniae may be an important pathogenic factor, which is closely related to hepatic abscess.

    Release date:2018-03-20 03:48 Export PDF Favorites Scan
1 pages Previous 1 Next

Format

Content