ObjectiveTo establish an evaluation index system suitable for key medical disciplines/specialties in Sichuan Province, with the coverage of tertiary-level comprehensive and tertiary specialty hospitals, and the provincial medical key disciplines/specialties as the starting point, so as to promote the development of key medical disciplines in Sichuan Province.MethodsThe literature method, expert meeting method, Delphi method, and analytic hierarchy process were used to establish the index system and the corresponding weights of each index.ResultsAn evaluation index system for the influence ranking of key medical disciplines/specialties in Sichuan Province was established, covering scientific and technological inputs and outputs, clinical services, and industry influence. The entire evaluation index system included 3 first-level indicators, 8 second-level indicators, 19 third-level indicators and corresponding weights.ConclusionThis evaluation index system has applied to rank the influence of key medical disciplines/specialties in Sichuan Province, laying a solid foundation for the influence evaluation of the key medical disciplines/specialties and the future platform construction in Sichuan Province.