目的 比较低频与高频探头超声对急性阑尾炎的诊断价值。 方法 对2010年1月－2011年6月120例急性阑尾炎的手术病理结果与超声检查结果进行回顾性分析，比较低、高频探头超声对急性阑尾炎的诊断价值。 结果 120例急性阑尾炎中，通过低频探头超声检出67例（55.8%），通过高频探头超声检出105例（87.5%）；单纯性阑尾炎以及化脓性和坏疽性阑尾炎高频探头超声检出例数明显大于低频探头超声，差异有统计学意义（P＜0.05）；阑尾周围脓肿低、高频探头超声均全部检出。 结论 高频探头超声对急性阑尾炎的检出率高于低频探头超声，但二者各有所长，在临床中联合应用能有效提高急性阑尾炎的超声诊断符合率。
Objective To systematically review the association between prothrombin gene G20210A mutation and the risk of cerebral venous thrombosis (CVT). Methods Databases including PubMed, Springer, Google Scholar, The Cochrane Library (Issue 1, 2016), CNKI, WanFang Data and CBM were searched for case-control studies concerning the association between prothrombin gene G20210A mutation and cerebral venous thrombosis risk from inception to January 2016. Two reviewers independently screened literature, extracted data and assessed the risk of bias of included studies. Then, meta-analysis was performed using RevMan 5.3 software and Stata 12.0 software. Results A total of 26 case-control studies were included, involving 1 361 CVT cases and 6 323 controls. The results of meta-analysis showed that: there was a significant association between prothrombin gene G20210A mutation and CVT risk (OR=4.56, 95% CI 3.51 to 5.93,P<0.000 01). Sensitivity analysis showed no significant publication bias was detected confirmed the stability of results. Subgroup analysis showed that G20210A mutation increased CVT risk in adults (OR=5.02, 95% CI 3.81 to 6.60,P<0.000 01), but not in children (OR=1.99, 95% CI 0.83 to 4.79,P=0.12). Conclusion Prothrombin gene G20210A mutation can significantly increase the CVT risk. Due to the limited quality and quantity of included studies, the above results are needed to be validated by more high quality studies.