ObjectiveTo summarize recent progress of minimally invasive diagnosis and treatment of patients with choledocholithiasis.Method The literatures relevant to progress of minimally invasive diagnosis and treatment of patients with choledocholithiasis at home and abroad in recent years were summarized and reviewed. ResultsThe preoperative diagnosis of patients with choledocholithiasis was very important, and it still needed to combine with the clinical symptoms, biochemical indicators, and imaging examination and so on. Combined or single application of laparoscopy, endoscopy, biliary endoscopy to reflect their respective advantages in the treatment of choledocholithiasis, it had become the most important minimally invasive treatment method. ConclusionEarly diagnosis and proper minimally invasive approach are important for good therapeutic efficacy, and realize modern surgical idea for damage control and rapid recovery.
ObjectiveTo understand the latest research progress of long noncoding RNAs (lncRNAs) in occurrence and development mechanisms of common digestive system neoplasms. MethodLiteratures about regulated occurrence and development mechanisms of digestive system neoplasms by lncRNA were reviewed according to the results searched from PubMed. ResultsThere were three main function modes (decoy, guide, and scaffold) of the lncRNAs, which could regulate proliferation, apoptosis, invasion, and metastasis of the digestive system neoplasms, such as gastrointestinal cancer, liver cancer, and pancreatic cancer through the mechanisms of the epigenetic regulation, transcription regulation, and posttranscription regulation. ConclusionsThe functions and tumorigenic mechanisms of the most lncRNAs are not entirely clear. The functions of lncRNAs played in the digestive system neoplasms needs to be understood, which might contribute to new tumor biomarker detection and effective treatment strategies.