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find Keyword "Portopulmonary hypertension" 1 results
  • Sildenafil for Portopulmonary Hypertension: A Case Report and Literature Review

    Objective To observe the efficacy and safety of sildenafil in one case of PoPH patients. Methods A case of PoPH patient who was successfully treated with sildenafil was retrospectively analyzed,and literatures related sildenafil and PoPH were reviewed. Results A case of PoPH patient admitted with dyspnea on extetion was diagnosed with echocardiography,gastroscrope and other examinations. She was treated with sildenafil and responded well by decreased pulmonary arterial pressure,improved exercise tolerance and life quality,without obvious side effects. Literatures review suggested that PoPH is an under-recognized but life-threatening complication of cirrhosis or noncirrhotic portal hypertension with poor prognosis which exists in decompensated chronic liver diseases patients. The most classic symptoms of PoPH is progressive dyspnea on extertion. PoPH patients may benefit from sildenafil therapy with decreased pulmonary arterial pressure and improved life quality. Conclusions Theawareness of PoPH should be increased and Sildenafil may be effective and safe for PoPH patients. However,more evidences from clinical trials are needed.

    Release date:2016-08-30 11:58 Export PDF Favorites Scan
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