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find Keyword "Prediction models" 2 results
  • Predictive model for the risk of postpartum depression: a systematic review

    ObjectiveTo systematically evaluate postpartum depression risk prediction models in order to provide references for the construction, application and optimization of related prediction models. MethodsThe CNKI, VIP, WanFang Data, PubMed, Web of Science and EMbase were electronically searched to collect studies on predictive model for the risk of postpartum from January 2013 to April 2023. Two reviewers independently screened the literature, extracted data, and assessed the quality of the included studies based on PROBAST tool. ResultsA total of 10 studies, each study with 1 optimal model were evaluated. Common predictors included prenatal depression, age, smoking history, thyroid hormones and other factors. The area under the curve of the model was greater than 0.7, and the overall applicability was general. Overall high risk of bias and average applicability, mainly due to insufficient number of events in the analysis domain for the response variable, improper handling of missing data, screening of predictors based on univariate analysis, lack of model performance assessment, and consideration of model overfitting. ConclusionThe model is still in the development stage. The included model has good predictive performance and can help early identify people with high incidence of postpartum depression. However, the overall applicability of the model needs to be strengthened, a large sample, multi-center prospective clinical study should be carried out to construct the optimal risk prediction model of PPD, in order to identify and prevent PPD as soon as possible.

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  • Predictive model for the risk of knee osteoarthritis: a systematic review

    ObjectiveTo systematically evaluate the risk prediction model of knee osteoarthritis (KOA). MethodsThe CNKI, WanFang Data, VIP, PubMed, Embase, Web of Science and Cochrane Library databases were electronically searched to collect relevant studies on KOA’s risk prediction model from inception to April, 2024. After studies screening and data extraction by two independent researchers, the PROBAST bias risk assessment tool was used to evaluate the bias risk and applicability of the risk prediction model. ResultsA total of 12 studies were included, involving 21 risk prediction models for KOA. The number of predictors ranged from 3 to 12, and the most common predictors were age, sex, and BMI. The range of modeling AUC included in the model was 0.554-0.948, and the range of testing AUC was 0.6-0.94. The overall predictive performance of the models was mediocre and the risk of overall bias was high, and more than half of the models were not externally verified. ConclusionAt present, the overall quality and applicability of the KOA morbidity risk prediction model still have great room for improvement. Future modeling should follow the CHARMS and PROBAST to reduce the risk of bias, explore the combination of multiple modeling methods, and strengthen the external verification of the model.

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