Objective To assess the value of fluorine-18 fluorodeoxyglucose （18 F-FDG） positron emission tomography （PET） in patients with pulmonary tuberculosis. Methods Fifty-three patients with pulmonary tuberculosis were imaged with 18SF-FDG-PET. 18F-FDG-PET data were analyzed retrospectively with visual method and semiquantitative method. When pulmonary tuberculosis with abnormal 18F-FDG uptake appeared in PET scans confirmed by visual method, their maximum standard uptake value （SUVmax）, mean standard uptake value （SUVmean） and standard uptake value of normal lung （SUVlung） were measured using semiquantitative method. Results Thirty-six pulmonary tuberculous nodules could be detected by 18SF- FDG-PET, and were diagnosed active tuberculosis with visual method. SUVmax（2. 77±1. 20） and SUV mean（2.15±0.86） were higher than SUVlung（0.41± 0.09, Z=-5. 232, P〈0.01 ; Z=- 5. 232, P〈0.01）. Correlations were not found between SUVmax ,SUVmax and nodule size （Dmax, Dmin）, SUVlung, age, blood glucose level in these 36 patients （P〉0.05）. Seventeen fibrosis and calcification cases without caseous necrosis were not found abnormal in 18F-FDG-PET. Conclusion 18F- FDG- PET is useful in diagnosing active tuberculosis , extent of tuberculosis and guiding therapeutic regimen.
Abstract:Objective To investigate the application value of fluorine-18 fluorodeoxyglucose （18F-FDG）- positron emission tomography （PET） in patients with esophageal cancer. Methods From October 1999 to December 2005, 52 patients with esophageal cancer （15 untreated and 37 treated patients） were imaged with 18F-FDG-PET.18F-FDG-PET scans were analyzed by visual method combined with semiquantitative analysis. 18F-FDG- PET results were compared with pathological results and follow-up survey. Results There were 15 untreated patients before 18F-FDG-PET scans, the primary tumors in 11 patients （T2 to T4 stage） were all 18F-FDG avid and primary site in 4 patients （T1 stage） showed nothing abnormal. The sensitivity of 18F-FDG-PET was 73.3% （11/ 15）. In diagnosing 16 resected enlarged lymph nodes beyond 1 cm in 8 operated patients. Six lymph nodes was malignant by 18F-FDG-PET scans before operation, there were 5 metastases lymph nodes and 1 tuberculosis nodes. 18F-FDG-PETrevealed distant metastases in 7 patients and corrected them from surgery candidates to late stage. In 37 treated patients 18F-FDG-PET confirmed 34 patients with recurrence and/or metastasis. Conclusion ^18F-FDG-PET has limited value in comfirming T and N stage in esophageal cancer. It shows much value in M stage and treatment guiding in patients with esophageal cancer.