This article reported the implantation of the greater auricular nerve into the cervicoshoulder skin flap in rabbits. The progress following implantation of the nerve was continuously observed. According to the time elapsed from the nervesbeing implanted, the experimental animals were divided into 4 groups, 4 animalsin each group, in the order of 1, 2, 4 and 6 months groups, respectively, and the normal skin and the cervicoshoulder skin flaps without nerve implantation were used as control. The electron microscope was the method used to observed theprogress. The results showed that in the 2nd month the unmyelinated fibers first appeared, then the myelinated in the 4th month. The caliber of the axons, the thickness of the myelin sheath and the ratio of MF/UF increased with time. In the 4th month, the number of the regenerating nerve fibers (unmyelinated fibers predominant) had achieved the highest level and significantly exceeded that of thenormal skin. But at the 6 months. the MF/UF ratio was still for lower than normal.
Basing on the experimental results, 48 nerve defects (with the length of 3-4 cm in 21 cases, 4.1-5cm in 25 cases and 6cm in 2 cases) were repaired clinically by using vaseularized nerve sheath canal with living Schwann s cells, 87.5 percent of them obtained good results. The advantages were: (1) The neural sheath had rich blood supply with resultant less scar from its healing; (2) The living Schwann s cells would secrete somatomedin to promote the reproduction of neural tissues; and (3) The useless neurofib...
The model of the denervated lateral head of gastrocnemius musde was adopted in this experiment on 50 rabbits. At random, the denervated muscle on oneside received the soleus muscle bundles with neurovascular pediele implantation (MBNPI). While the other side received the direct soleus nerve implantation (DNI). Eighteen weeks later after the two types of implantations the electromyography, force of muscles, histochmical findings and the electronic microscopic examination of the dernervated muscles of the two...