Abstract: Air leak is still a common postoperative complication after selective lobectomy. The majority of patients undergoing lobectomy have some risk factors of postoperative air leak or persistent air leak. Nowadays,preventive measures of postoperative air leak mainly include preoperative, intraoperative (surgical technique,reinforcement material,pleural cavity reduction),and postoperative (pleurodesis,chest drainage management) strategies. Many of these new measures have been applied in clinical practice with satisfactory outcomes.