ObjectiveTo systematically review the efficacy of Chinese medicine for endometrial hypoplasia. MethodsDatabases such as PubMed, EMbase, MEDLINE (Ovid), The Cochrane Library (Issue 8, 2014), CNKI, VIP and WanFang Data were searched for randomized controlled trials (RCTs) and quasi-RCTs concerning the efficacy of Chinese medicine for endometrial hypoplasia up to August 2014. According to the inclusion and exclusion criteria, two reviewers screened literature, extracted data, and assessed methodological quality of included studies. Then meta-analysis was performed using RevMan 5.3 software. ResultsA total of 5 RCTs and 6 quasi-RCTs involving 914 patients were included. The results of meta-analysis showed that Chinese medicine group was superior to control group in endometrial thickness (MD=0.86, 95%CI 0.35 to 1.37, P=0.000 01), clinical pregnancy rates (RR=2.62, 95%CI 2.02 to 3.38, P<0.000 01), endometrial morphous (RR=1.23, 95%CI 1.06 to 1.42, P=0.005), PI of uterine artery blood flow (MD=-0.54, 95%CI -0.80 to -0.28, P<0.000 1), RI of uterine artery blood flow (MD=-0.12, 95%CI -0.17 to -0.08, P<0.000 1), and estradiol level (MD=96.03, 95%CI 44.32 to 144.74, P=0.003); However, the two groups were alike in progesterone level without significant difference (MD=2.00, 95%CI -0.64 to 4.65, P=0.14). ConclusionCurrent evidence indicated that, Chinese medicine is beneficial for endometrial hypoplasia. Due to limited quantity and quality of the included studies, the above conclusion still needs to be verified by conducting more high quality studies.