Abstract: Currently, there are two significant tendencies in the advancement and progress of video-assisted thoracoscopic surgery(VATS), firstly, the widening surgical indications for VATS techniques, and secondly, the use of single-port VATS which is less invasive and more cosmetic. This article focuses in particular on four aspects of single-port VATS, including;(1)the individualized incision approach and its characteristics of single-port VATS;(2)single-port VATS for the treatment of pneumothorax and the development of related techniques and equipment;(3)single-port VATS for the diagnosis and treatment of thoracic diseases such as lung lobectomy;(4)the advantages and disadvantages of single-port VATS in clinical practice.