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find Author "TANG Guangcai" 1 results
  • Diffusion Weighted Imaging Diagnosing Cystic Meningioma

    目的 探讨囊性脑膜瘤的磁共振表现、表观弥散系数(ADC)图的影像特点、ADC值与病理分级的关系及ADC值对判断不同病理亚型脑膜瘤的价值。 方法 回顾性分析2003年3月-2007年12月18例经病理证实的囊性脑膜瘤患者的磁共振表现,其中男8例,女10例,平均年龄45.6岁。在ADC图上分别测量肿瘤实质、瘤周水肿、囊变区的平均ADC值(均取4~6个区域,取平均值),比较不同病理亚型、不同病理分级的肿瘤实质、瘤周水肿、囊变区的ADC值差异是否有统计学意义。 结果 良恶性脑膜瘤肿瘤实质ADC值差异无统计学意义(P>0.05);囊性脑膜瘤各亚型间的肿瘤实质、瘤周水肿的ADC值差异无统计学意义(P>0.05);肿瘤实质、囊变区与瘤周水肿平均ADC值相比差异均有统计学意义(P<0.05)。 结论 ADC值可区分肿瘤实质、囊变区及瘤周水肿,但对脑膜瘤亚型及良恶性的甄别需结合常规MRI与增强的征象。Objective To explore the MRI imaging manifestation, features of apparent diffusion coefficient (ADC) map and the relationships among ADC value, pathologic grading and pathologic subtype of cystic meningioma. Methods The clinical data of 18 patients (8 males and 10 females, with an average age of 45.6 years) with cystic meningiomas confirmed by pathologically examination were retrospectively analyzed. The ADC values of tumor parenchyma, peritumoral edema, cystic regions and the contralateral normal brain of the tumor parenchyma were measured and analyzed.The ADC value of the tumor parenchyma, peritumoral edema, cystic region were measured and then compared with the pathological findings. P value of less than 0.05 was considered as having a statistically significant difference. Results There was no significant difference in ADC values between benign and malignant meningioma and also among the tumor parenchyma, periedema and cystic region in different pathological subtypes. The difference in ADC values amongst tumor parenchyma, peritumoral edema and cystic region were statistically significant (P<0.05). Conclusions Although ADC quantitative measurement allows the differentiation of the tumor parenchyma, cystic region and peri-edema, it is need to combined with conventional MR examination to assess tumor malignancy as well as grading in cystic meningioma.

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