目的 探讨英夫利西单抗治疗克罗恩病（CD）在临床护理中的有效管理措施。 方法 对2011年9月—2012年8月静脉输注英夫利西单抗的25例住院患者，在药物配伍、输注流程、配制方法等方面予以严格管理，并严密观察药物不良反应和积极做好健康宣教。 结果 经过精心的观察、护理和有效的护理管理措施，25例患者用药6周后体温恢复正常，大便次数1～2次/d，大便隐血试验阴性，腹痛、腹胀症状缓解，体重增加2～7 kg。 结论 在英夫利西单抗药物临床输注过程中，实施有效的输注护理管理措施是确保患者治疗安全以及提高护理质量的重要保障。
目的 探讨护理行为对重症急性胰腺炎患者在实时强化血糖控制和治疗中的效果与影响。 方法 选择2010年7月－2011年7月15例采用强化血糖控制研究的急性重症胰腺炎患者，对其实时24 h动态血糖监测的护理方法及要点进行回顾分析。 结果 15例患者顺利完成强化血糖控制的临床研究，血糖值达到目标监测范围（6.1～8.3 mmol/L）的百分比例78.3%，未出现严重并发症。 结论 实时动态的血糖监测、严格执行的强化血糖控制方案及针对性护理措施可为重症胰腺炎患者的血糖强化控制提供安全有效的保证。
【摘要】 目的 探讨机械法准分子激光角膜上皮瓣下磨镶术（Epi-LASIK）对大视杯高度近视患者的视网膜神经纤维层 （RNFL）的影响。 方法 对2007年1月-2009年1月拟行Epi-LASIK手术的眼底杯盘比gt;0.5的44例44只眼行光相干断层扫描（OCT）检查，测量以视盘为中心、直径为3.4 mm的RNFL厚度， 以象限图分4个区域（上方、下方、颞侧、鼻侧）显示。并分别于手术前及手术后第10 天，1、3 个月，1、2年进行随访。对所测数据进行方差分析。 结果 RNFL厚度测量结果显示， 手术前上方、下方、鼻侧、颞侧RNFL厚度与手术后比较， 差异均无统计学意义（Pgt;0.05）。 结论 Epi-LASIK手术对大视杯近视的RNFL厚度无明显影响。【Abstract】 Objective To investigate the effects of Epi-LASIK on retinal nerve fiber layer (RNFL) thickness in patients with large cup. Methods Forty-four patients (44 eyes) with high myopia from January 2007 to January 2009, whose C /D area ratios were above 0.5, underwent optical coherence tomography(OCT)examination. To measure the RNFL thickness taking optic disk as the center, diameter as 3.4 mm, for quadrant graph as above, below, temporal, lateral. After the operation in the first 10 days, and one, three months, and one, two years after surgery were followed. The data were analyzed by analysis of variance. Results The RNFL thickness at every quadrant had no statistical significant difference between preoperative period and postoperative time(Pgt;0.05). Conclusion Epi-LASIK surgery has no effect on RNFL thickness in high myopic patients with large cup.
In recent years, an increasing amount of systematic reviews have been published; however, few reviews adequately considered and reported details of interventions, which not only limited the usability of systematic reviews but also wasted resource. In order to improve reporting of intervention details in systematic reviews, BMJ recently published recommendations. This paper interprets the recommendations to improve usability of systematic reviews.
ObjectiveTo systematically review the association between migraine and lacunar infarcts on MR image.MethodsPubMed, EMbase, The Cochrane Library, CNKI, VIP and WanFang Data databases were electronically searched to collect randomized controlled trials, cohort studies and cross-sectional studies on the association between migraine and lacunar infarcts from inception to March 2019. Two reviewers independently screened literature, extracted data and assessed the risk of bias of included studies, then, meta-analysis was performed by RevMan 5.3 software.ResultsA total of 5 studies involving 5 104 participants were included. The results of meta-analysis showed that: there were no significant associations of migraine (OR=0.93, 95%CI 0.78 to 1.12, P=0.470) and aura (OR=1.10, 95%CI 0.89 to 1.36, P=0.390) with lacunar infarcts on MR image. Subgroup analysis by age, presence or absence of aura showed no significant tendency.ConclusionsThere is no significant relationship between migraine and lacunar infarcts. Due to limited quality and quantity of the included studies, more high quality studies are required to verify above conclusions.
ObjectiveTo analyze the research status and summarize research hotspots and development trends of research on artificial intelligence in stomatology. MethodsData retrieved from the Web of Science Core Collection database from inception to 2021 were analyzed by CiteSpace software. ResultsThe number of publications about artificial intelligence in stomatology was rising. The United States ranked first in terms of publications and cooperation capabilities. Apart from comprehensive stomatology journals, the literature was mainly published by specialist journals of oral and maxillofacial surgery, orthodontic and dental radiology. Oral head and neck tumors were the frontier field of artificial intelligence research in stomatology. Artificial intelligence, including deep learning and neural networks, showed the tremendous potential medical value and economic value in assisting in the diagnosis and treatment decisions of oral diseases. ConclusionThe research of artificial intelligence in stomatology has rapidly increased, which is conducive to the development of stomatology in the direction of digitalization, intelligence, and individuation.
Poly(styrene-block-isobutylene-block-styrene) (SIBS) and its crosslinked product crosslinked polyisobutylene (xPIB) are a kind of novel thermoplastic elastomer. They have excellent biocompatibility and stability, which are suitable for long-term implantation in human body. At present, SIBS is widely used in cardiovascular diseases, and also has preliminary application in ophthalmology. This article reviews the application and research progress of SIBS and xPIB in ophthalmic glaucoma minimally drainage tube material, intraocular lens material, new sclera buckle material and orbital defect filler, with a view of providing reference for the clinical application of such biomedical materials in ophthalmology.
Sleep disorder is related to many comorbidities, such as diabetes, obesity, cardiovascular diseases, and hypertension. Because of its increasing prevalence rate, it has become a global problem that seriously threatens people’s health. Various forms of sleep disorder can cause increased insulin resistance and/or decreased sensitivity, thus affecting the occurrence, development and prognosis of diabetes. However, sleep health has not been paid attention to in recent years. Therefore, this article summarizes the findings of the correlation between sleep disorder and diabetes mellitus in recent years, by elaborating the relationship between various types of sleep disorder (including sleep apnea syndrome) and diabetes mellitus, as well as their mechanisms and intervention measures, in order to enhance the attention of clinical workers to sleep health, and to provide basis for reducing the risk of diabetes.
ObjectiveTo systematically review the epidemiological characteristics and economic burden of traumatic spinal cord injury (SCI) in China.MethodsPubMed, EMbase, WanFang Data, VIP and CNKI databases were electronically searched to collect studies of the epidemiological characteristics and economic burden of SCI in China from January 1st, 1978 to August 30th, 2017. Two reviewers independently screened literature, extracted data and assessed the risk of bias of included studies, then, meta-analysis was performed by using Stata 12.0 software.ResultsA total of 32 studies were included. The results of meta-analysis showed that: the prevalence of SCI in China was 37 persons per million per year (95%CI 21 to 53), with the average age ranged from 34.7 to 54.4 years. Men had a higher risk of SCI than Women. Motor vehicle collisions (MVCs) and falls were the two main causes of SCI. The neurological injury levels were varied, ASIA grade A was the most common and grade E was the least.ConclusionCurrent evidence shows that there is a high prevalence of SCI in China with heavy social and medical burden. The main reason of SCI is motor vehicle collisions and falls. Due to limited quality and quantity of the included studies, more high-quality studies are needed to verify above conclusion.