Abstract: Objective To evaluate the results of surgical treatment of tetralogy of Fallot in adults. Methods From July 2002 to August 2009,75 adult patients with tetralogy of Fallot received surgical treatment in Xijing Hospital, ForthMilitary Medical University.There were 35 males and 40 females, with age at l7 to 37 years (23.30±3.50 years), and eoperativehemoglobin at 143 to 231 g/L(172.00±31.00 g/L).All these patients were diagnosed by.echocardiograph before operation. All the patients were received tetralogy of Fallot of corrective operation in the hypothermia cardiopulmonary bypass. A total of 46 patients had a transannular right ventricular outflow tract patch,and 29 patients had a non ansannular patch. Results Operation time was 157 to 276 min(221.32±41.34 min), cardiopulmonary bypass time was 68 to 163 min(91.71±28.35 min) and aorta intercepted time was 37 to 96 min(55.47±23.61 min). There were 6 operative deaths with an operative mortality at 8.00%. The causes of death were low output syndrome(n=3),acute renal failure(n=2), and multiple organ failure(n=1).Nine patients needed reoperation for postoperative bleeding(12.00%).We followed up 69 patients from 3 to 56 months (26.31±7.40 months). There were 2 patients with trivial residual shunt. The cardiac function status were New York Heart Association(NYHA) Ⅰ to Ⅱ in the 69 patients.No late death occured. Conclusion The effectiveness of surgical treatment for adults with tetralogy of Fallot is satisfactory.