Objective Based on “timing it right”, the application effect of the continuous nursing program in school-age children with epilepsy. Methods A total of 80 epileptic children and primary caregiver who were admitted to the Department of Neurology of Wuxi a third class A children’s hospital from October 2022 to March 2023 were selected as the research objects, and were divided into experimental group and control group with 40 cases each by convenience sampling. The control group was given routine care, and the intervention group was given a continuous nursing for school-age children with epilepsy based on timing theory. The continuous nursing process was divided into four stages: diagnosis stage, treatment stage,preparation stage, and convalescence stage.According to the needs of the different stages of the disease,In each stage,the intervention was carried out from disease cognition, emotional support, Correct care, psychological adjustment, rehabilitation training. TO Reduce the burden on caregivers and promote the recovery of patients. The results of Knowledge of the disease, burden of Caregiver and quality of life were compared between the two groups before intervention, before discharge and Three months after discharge through Epileptic disease health knowledge questionnaire, Zarit Care-giver Burden Interview, PedsQTM4.0. Results After intervention, The degree of seizures-related knowledge mastered by the main caregivers of children with epilepsy, the quality of life were significantly improved (all P<0.05). Conclusion The implementation of the continuity nursing plan based on the timing theory can improve the knowledge level of the main caregivers of epilepsy children, improve their caring ability, and improve the quality of life of epilepsy children.