ObjectiveTo design and use adverse nursing events information management system to improve the quality of nursing for high-risk patients and guarantee nursing quality and safety. MethodAdverse nursing events information management system was started from January 2014. Two hundred cases assessed to be nursing adverse events cases from September to December 2013 were chosen to form the control group, and another 200 from the same period in 2014 were designated to be the observation group. Then we compared the two groups in terms of the onset time of nursing assessment, incidence of adverse nursing events and rate of missing reports. ResultsThe onset time of nursing assessment, incidence of adverse events, and the rate of missing reports were significantly lower in the observation group than the control group (P<0.05). ConclusionsThe application of adverse nursing events information management system can improve the quality of nursing management and promote the nursing quality and safety.