【摘要】 目的 利用首过时间技术进行全胰腺CT灌注扫描，了解正常胰腺CT灌注的特点。 方法 2006年6月-2007年3月， 64例正常胰腺患者行64排螺旋CT灌注扫描，测量胰头、胰体及胰尾的灌注值、强化峰值、达峰时间和血容量。分别按患者的性别、年龄及胰腺测量的部位分组，将灌注参数进行统计分析。 结果 ①男性胰腺的血容量高于女性（Plt;0.05），其余灌注参数在两性间差异无统计学意义（Pgt;0.05）。②41~60岁组的灌注值低于lt;40岁组和gt;60岁组；gt;60岁组的强化峰值高于41~60岁组；41~60岁组的达峰时间长于lt;40岁组；gt;60岁组的血容量高于41~60岁组（Plt;0.05）。③胰体和胰尾的灌注值高于胰头（Plt;0.05），其余灌注参数在胰腺不同部位差异无统计学意义。 结论 正常胰腺血流状况在不同性别、不同年龄段及不同部位存在差异，首过时间技术应用于正常胰腺能反映这些特征。【Abstract】 Objective To investigate the CT perfusion features of normal pancreas with first-pass technique with 64-MDCT. Methods Perfusion CT was performed on 64 patients with normal pancreas from June 2006 to March 2007. Four perfusion parameters, including perfusion, peak enhancement, time to peak, and blood volume, were obtained at the head, body and tail of the pancreas. Perfusion parameters were compared between different sexes, among different age groups and among different sites. Results ① Blood volume of male was significantly higher than that of female (Plt;0.05). ② The perfusion value in the age group of 41-60 was significantly lower than that in the age group of lt;40 and gt;60 (Plt;0.05). The peak enhancement in the age group of gt;60 was significantly higher than that in the age group of 41-60 (Plt;0.05). The time to peak in the age group of 41-60 was significantly longer than that in the age group of lt;40 (Plt;0.05). The blood volume in the age group of gt;60 was significantly higher than that in the age group of 41-60 (Plt;0.05). ③The perfusion values of the body and the tail were significantly higher than that of the head (Plt;0.05). Conclusion There are significant differences in the perfusion parameters between different sexes and among several age groups and sites. The first-pass technique of perfusion applied in normal pancreas can reflect these features.
Cardiac magnetic resonance T2* mapping technique is a gradient echoes relaxation recovery sequence, being used to measure the iron metabolism abnormality clinically, such as myocardial iron of hemorrhage in acute myocardial infarction reperfusion injury, transfusion-dependent anemia, hemochromatosis and so on, which is supposed to be the main quantitative evaluation method for myocardial iron overload or deficiency with critical clinical value. This paper summarizes the technical and post-processing points of cardiac magnetic resonance T2* mapping and its clinical applications in diseases related to abnormal myocardial iron metabolism.
ObjectiveTo investigate the high-resolution computed tomography (HRCT) signs of patients diagnosed with the coronavirus disease 2019 (COVID-19) and explore its evolution features during hospitalization.MethodsFrom January 17, 2020 to February 26, 2020, HRCT images from 15 COVID-19 patients were analyzed. All the patients had positive nucleic acid test results of SARS-CoV-2. The imaging features of initial and follow-up of each patient were reviewed and graded based on the severity of lung lesions.ResultsAmong the 15 COVID-19 patients, ground-glass opacity (GGO) was found in 14 cases. Six patients presented with consolidation and 3 with fibrosis. Five patients had multi-lobe involvement. Subpleural distribution pattern was present in 12 patients (80.0%) and peribronchovascular distribution pattern was present in 2 patients (13.3%). The severity score on HRCT images at the follow-up was significantly higher than that at the initial (4.6±3.4 vs. 3.5±2.5, P=0.018 2). Increase of random distribution pattern (5 cases) were also noted at the follow-up.ConclusionsChest HRCT of COVID-19 patients is characterized with GGO mainly distributed in subpleural areas and a rapid progression within a short time interval. HRCT could provide a sensitive monitor to observe disease progression for COVID-19 patients.