【摘要】 目的 探讨经尿道等离子双极电切术（PKRP）治疗前列腺增生的安全性及临床疗效。 方法 2009年2-12月，采用PKRP治疗前列腺增生患者76例，记录手术时间、手术疗效及术后并发症。 结果 患者手术时间35～130 min，平均55 min。术中失血60～150 mL，均未输血。手术切除前列腺质量18～72 g。无直肠和膀胱穿孔，无电切综合征（TURS）及闭孔神经反射发生，无一例发生真性尿失禁，无死亡。术后随访2～6个月，IPSS评分平均为9分，最大尿流率平均为16.7 mL/s。 结论 PKRP是治疗前列腺增生的理想方法之一。【Abstract】 Objective To evaluate the efficacy of transurethral plasmakinetic resection of the prostate (PKRP) on benign prostatic hyperplasia. Methods A total of 76 patients with benign prostatic hyperplasia from February to December 2009 were treated with PKRP. The operative duration, therapeutic effect and postoperative complications were observed and recorded. Results The operative duration ranged from 35 to 130 minutes (average 55 minutes).The intraoperative blood loss was 60-150 mL, and no one needed transfusion.The prostate gland excised weight was 18-72 g. There were no intestinal and bladder perforation, no transurethral resection syndrome (TURS) or obturator nerve reflex occurs, and no urinary incontinence or death.IPSS score was nine and the maximal average uroflow was 16.7 mL/s during the 2-6 month follow-up. Conclusion PKRP is one of the ideal methods treating benign prostatic hyperplasia, especially for high-risk patients with benign prostatic hyperplasia.
Magnetic ferrite nanoparticles (MFNPs) have great application potential in biomedical fields such as magnetic resonance imaging, targeted drugs, magnetothermal therapy and gene delivery. MFNPs can migrate under the action of a magnetic field and target specific cells or tissues. However, to apply MFNPs to organisms, further modifications on the surface of MFNPs are required. In this paper, the common modification methods of MFNPs are reviewed, their applications in medical fields such as bioimaging, medical detection, and biotherapy are summarized, and the future application directions of MFNPs are further prospected.