Objective To assess the trend of prevalence, awareness, treatment and control rate of diabetes among elderly residents (≥45 years old) of Shunqin District in Nanchong City, and provide scientific references for the prevention and control of diabetes. Methods From February 2013 to August 2015, a cross-sectional survey was conducted in 9 sub-district offices of Shunqing District of Nanchong City. Households as a unit, the questionnaires and blood tests were investigated by clustering sampling in residents aged ≥45 years old. Results A total of 82 225 residents with complete information were enrolled in this study. Among them, 11 857 were with diabetes, in whom 6 260 had been diagnosed as diabetes before, only 5 054 were under treatment, and only 1 986 could control blood glucose to target level. The prevalence of diabetes was 14.4% among the participants. The rate of awareness, treatment, and control of diabetes in the 11 857 diabetes patients identified was 52.8%, 42.6%, and 16.7%, respectively. Conclusions The prevalence rate of diabetes is high, but the rate of awareness, treatment, and control of diabetes is low. It is necessary to popularize the knowledge and the cognition of diabetes, and it is urgent to make efficient measures to prevent and control diabetes in Nanchong City.
Objective To extend its application in the field of bone repair by adding oxygen-carboxymethylated chitosan (O-CMC) and gentamicin for modification of the calcium sulfate cement (CSC). Methods The O-CMC/CSC was prepared by adding O-CMC with different concentrations (0.1wt%, 0.3wt%, 0.5wt%, 0.7wt%, and 1.0wt%) in the CSC liquid phase. The effect of O-CMC on the CSC was evaluated by testing the injectability, compressive strength, degradation rate, pH value, cytotoxicity and osteogenesis. After the optimal concentration of O-CMC was determined, gentamicin with different concentrations (0.5wt%, 1.5wt%, and 2.5wt%) was added in the O-CMC/CSC, and then the compressive strength and antibacterial properties were investigated. Results After adding O-CMC in the CSC liquid phase, the injection time of O-CMC/CSC was increased to more than 5 minutes; it significantly prolonged with increased concentration of O-CMC (P<0.05). The compressive strength of the modified bone cement was in the range of 11-18 MPa and it was the highest when the concentration of O-CMC was 0.5wt% (P<0.05). The degradation rate of O-CMC/CSC was not influenced obviously by O-CMC (P>0.05). The pH value was in the range of 7.2-7.4 and Ca2+ concentration was in the range of 6-8 mmol/L.In vitro mineralization experiment indicated that the induced mineralization ability of O-CMC/CSC was much higher than that of pure CSC. The 0.5wt% O-CMC/CSC had the best performance; the compressive strength of the composite bone cement was above 5 MPa after gentamicin was added, which had antibacterial effect. Conclusion O-CMC is able to effectively improve the injection, compressive strength, and osteogenic activity of CSC; in addition, antibacterial properties is obtained in the CSC after adding gentamicin.