west china medical publishers
Author
  • Title
  • Author
  • Keyword
  • Abstract
Advance search
Advance search

Search

find Author "YuWuzhong" 1 results
  • Effects of Levocarnitine on Nutritional and Microinflammatory State in Maintenance Hemodialysis Patients

    ObjectiveTo observe the effects of levocarnitine by intravenous injection on nutritional and microinflammatory state in maintenance hemodialysis patients. MethodsBetween October 2010 and October 2011, 62 maintenance hemodialysis (>6 months) patients in our dialysis center were enrolled in this study, and were randomly divided into treatment group (n=32) and control group (n=30). Patients in the treatment group were injected with levocarnitine (1.0 g once) after every dialysis for 3 months, while patients in the control group only accepted routine hemodialysis therapy. Blood biochemical indicators, serum high sensitive C-reactive protein (hs-CRP) were measured and compared at the experiment onset and 3 months later. ResultsAfter treatment with levocarnitine for three months, the average serum levels of albumin (Alb), hemoglobin (Hb), triacylglycerol (TG), high density lipoprotein cholesterol (HDL-C) and hs-CRP, and the conditions of dialysis hypotension, muscular spasm, lacking in strength, and anorexia were significantly different between the two groups (P<0.05). But there was no significant difference in total cholesterol (TC) and low density lipoprotein cholesterol (LDL-C) between the two groups (P>0.05). For the control group, after treatment, Alb, Hb and condition of anorexia changed significantly (P<0.05), while TC, TG, LDL-C, HDL-C, hs-CRP, conditions of dialysis hypotension, muscular spasm and lacking of strength did not change (P>0.05); for the treatment group, after treatment, all Alb, Hb, TG, HDL-C, hs-CRP, conditions of dialysis hypotension, muscular spasm, lacking of strength and anorexia changed significantly (P<0.05), while TC and LDL-C did not change obviously (P>0.05). ConclusionLevocarnitine can significantly improve the nutritional and microinflammatory state and better the quality of life in maintenance hemodialysis patients.

    Release date: Export PDF Favorites Scan
1 pages Previous 1 Next

Format

Content