Objective To explore the application effect of " dual-channel teaching” of the rain classroom platform in airway obstruction teaching. Methods A total of 228 nursing undergraduate students in Grade 2015 were selected as the research subjects by the method of cluster random sampling. Class B (n=115) was randomly selected as the control group and Class A (n=113) was selected as the experimental group. Class B adopted the traditional practical teaching mode, and Class A was integrated with the rain classroom platform on this basis. After the end of the course, the learning situation of the experimental group students were understood through the rain classroom background data, the teaching effects of the two groups were evaluated by the students’ theoretical scores and applied case test scores, and the experimental group student’s evaluation of the rain class was understood by questionnaire survey. Results There were 105 nursing students (92.92%) completing pre-school preparation tasks, 103 (91.15%) participating in the class answering, and 113 (100.00%) completing the after-school exercises. The theoretical scores and applied case assessment scores of the experimental group students were 79.44±6.25 and 83.24±3.64, respectively, and those of the control group students were 68.50±7.96 and 70.59±5.51, respectively, the differences between the two groups were statistically significant (P<0.05). In the experimental group, 92 nursing students (81.42%) liked the rain classroom platform teaching. Conclusion The rain classroom platform teaching can bring about the ecological transformation of the open speech in classroom, and comprehensively improve the overall quality and comprehensive ability of students, which is worthy of promotion and application in teaching.
Objective To understand the current situation of healthcare-associated infection (HAI) in comprehensive hospitals with a number of beds≥900, and provide a reference for the next step in formulating HAI prevention and control measures. Methods The data on the prevalence rate of HAI in comprehensive hospitals with a number of beds≥900 of Yunnan Province between 2020 and 2022 were retrospective collected. The HAI situation and trend in each year were analyzed. Results A total of 119 comprehensive hospitals were included, with 166 745 patients surveyed and 3 237 cases of HAI. Lower respiratory tract infection and urinary tract infection were the most common sites. The department with the highest incidence of hospital infections was the intensive care unit, followed by neurosurgery and hematology. The prevalence rates of HAI showed a downward trend from 2020 to 2022 (2.08% vs. 1.99% vs. 1.79%, χ2=14.301, P<0.001). A total of 1 315 strains of hospital-acquired pathogens were detected, all of which were mainly Gram-negative bacteria, with Escherichia coli and Klebsiella pneumoniae being more common. The rate of antibiotics use and the rate of pathogen testing showed an upward trend from 2020 to 2022 (χ2=79.233, 23.866, P<0.001), the infection rate of incision site and the prophylactic use rate of antimicrobial drugs in patients with class Ⅰ surgery both showed a decreasing trend (χ2=15.551, 6.311, P<0.05). Conclusions The prevalence of infection in comprehensive hospitals of Yunnan Province is decreasing. But the supervision of key departments, the implementation of pathogen prevention and control measures, and the rational use of antibiotics in inpatients are still the focus of future work.
Objective To assess the association between MTHFR C677T polymorphism and gastric cancer in Chinese population. Methods Relevant literatures were searched from PubMed, EMBASE, Web of Science, China Biology Medicine Database, Chinese Science and Technology Academic Journal, Chinese Journal Full-Text Database, and Wanfang database, the period ranged from their inception to June 2016, and then meta analysis was performed by Stata 10.0 software. Results A meta-analysis of 13 case-control studies enrolled was performed, including 2 569 gastric cancer patients and 3 495 controls. Results of meta-analysis showed that, in Chinese population, CC was a protective factor for gastric cancer comparing with CT 〔OR=0.75, 95% CI is (0.67, 0.85), P=0.001〕 , CT was a protective factor for gastric cancer comparing with TT 〔OR=0.77, 95% CI is (0.68, 0.89), P=0.001〕 , CC was a protective factor for gastric cancer comparing with TT 〔OR=0.56, 95% CI is (0.49, 0.65), P=0.02〕 , CC was a protective factor for gastric cancer comparing with CT+TT 〔OR=0.68, 95% CI is (0.61, 0.76), P=0.001〕 , CC+CT was a protective factor for gastric cancer comparing with TT 〔OR=0.73, 95% CI is (0.60, 0.89), P=0.002〕 . Conclusion There is association between MTHFR C677T polymorphism and gastric cancer in Chinese population.