ObjectiveTo discuss the effect of synthesized physical nursing care on the treatment of meibomian gland dysfunction (MGD) patients. MethodWe collected 100 MGD patients between March and September 2014, and randomized them into conventional and synthesized physical nursing care groups with 50 patients in each. We evaluated the subjective symptoms, the break-up time of tear-film and the function of lacrimal gland secretion before and after treatment. We surveyed the satisfaction of these patients during the follow-up. ResultsCompared with the conventional nursing care group, the synthesized group had less clinical symptoms, longer break-up times of tear-film and better lacrimal gland secretion function. The results showed remarkable statistical significance (P<0.05). ConclusionsSynthesized nursing care has significant effect on the treatment efficacy of MGD outpatients.