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find Author "ZHOU Wenjun" 3 results
  • Research progress on risk factors for acute aortic dissection complicated with acute lung injury

    Acute lung injury is one of the common and serious complications of acute aortic dissection, and it greatly affects the recovery of patients. Old age, overweight, hypoxemia, smoking history, hypotension, extensive involvement of dissection and pleural effusion are possible risk factors for the acute lung injury before operation. In addition, deep hypothermia circulatory arrest and blood product infusion can further aggravate the acute lung injury during operation. In this paper, researches on risk factors, prediction model, prevention and treatment of acute aortic dissection with acute lung injury were reviewed, in order to provide assistance for clinical diagnosis and treatment.

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  • Employment Intentions to Primary Health Service Organizations among Medical Students in North Sichuan Medical College: A Questionnaire Survey

    Objective To get known about the employment intentions to primary health service organizations (PHSO) among medical students in North Sichuan Medical College, and to assess its main influencing factors, so as to provide scientific evidence for occupational guidance in medical colleges, as well as talent introduction and retention in PHSO. Methods By cluster sampling method, medical undergraduates and college students in North Sichuan Medical College were investigated using a self-designed questionnaire from April to October, 2010. EpiData 3.1 and SPSS 16.0 software were used for inputting data and analyzing respectively. Results a) Among 900 questionnaires distributed, 870 were reclaimed (response rate 96.7%). b) Nearly 60% of medical students thought their own professional development was “average”, with following intentions after graduation in order: employment first and then postgraduate entrance exam, employment, postgraduate entrance exam; and 85% of medical students were more willing to work in medical institutions above level-2 in city or county. c) More than 70% of medical students’ employment intentions to PHSO were “average”, and “unwilling”, etc.; the main influencing factors were personal development space, salary and welfare, and comprehensive strength of hospital, etc. d) More than 90% of medical students “Do not know” or “generally” understood the related national preferential policies. Conclusion Government, PHSO and universities should take measures together and increase policy advocacy and infrastructure investment, so as to encourage medical students to work in PHSO.

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  • Prognosis of acute gastrointestinal injury in patients early after acute type A aortic dissection repair and the Nomogram prediction model development

    Objective To analyze the risk factors and prognosis of acute gastrointestinal injury (AGI) early after acute type A aortic dissection (ATAAD) repair, and develop the Nomogram prediction model of AGI. Methods The patients who underwent ATAAD cardiopulmonary bypass surgery in our hospital from 2016 to 2021 were collected and divided into an AGI group and a non-AGI group. The clinical data of the two groups were compared. A Nomogram prediction model was established by using R language. Results A total of 188 patients were enrolled, including 166 males and 22 females, aged 22-70 (49.70±9.96) years. Through multivariate logistic regression analysis, the aortic dissection (AD) risk score, poor perfusion of superior mesenteric artery (SMA), duration of aortic occlusion and intraoperative infusion of red blood cells were the predictors for AGI (P<0.05). There were statistical differences in the ventilator-assisted duration, ICU stay time, liver dysfunction, renal insufficiency, parenteral nutrition, nosocomial infection and death within 30 days after the operation between the two groups (P<0.05). The Nomogram prediction model was established by using the prediction factors, and the C index was 0.888. Through internal verification, the C index was 0.848. The receiver operating characteristic curve was used to evaluate the discrimination of the model, and the area under the curve was 0.888. Conclusion The AD risk score after ATAAD, poor perfusion of SMA, duration of aortic occlusion and intraoperative infusion of red blood cells are independent predictors for AGI. The Nomogram model has good prediction ability.

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