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find Keyword "antiparasitic chemotherapy" 1 results
  • Progress in medical treatment of echinococcosis

    Echinococcosis was a zoonotic disease that seriously threatened human health. The disease was widely distributed in China, and was distributed in Tibet Autonomous Region, Qinghai Province, Xinjiang Uygur Autonomous Region, Sichuan Province, and other places, which had become a social and economic burden in China. Human beings were mainly infected with alveolar echinococcosis (AE) and cystic echinococcosis (CE), which mainly involved liver, lung, brain, bone and other organs or tissues. The surgical resection was the first line treatment, and antiparasitic agents therapy was the main supplementary or salvage treatment methods. Currently, classic drugs mainly included Albendazole and Praziquantel, which used alone or in combination. There were also some attempts to treat echinococcosis, including broad-spectrum anti infective drugs such as nitrozotocin, cell proliferation inhibiting drugs such as bortezomib, metabolic drugs such as metformin, or traditional medicines such as Artemisinin. It wss also suggested to adopt a cancer management model for echinococcosis, and the imaging follow-up time for CE after antiparasitic chemotherapy should be at least 3 years, and for AE should be at least 10 years. More importantly, measures such as education and vaccine inoculation should be taken to actively prevent and control the occurrence and spread of echinococcosis.

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