Objective To investigate the clinical and imaging manifestations, laboratory examination, diagnosis, treatment and prognosis of hepatic tuberculosis, and improve the understanding of hepatic tuberculosis. Methods One case of hepatic tuberculosis that treated by author was reported, at the same time, the domestic literatures were retrieved from 2000 to 2015, 158 cases of hepatic tuberculosis were collected, and the clinical manifestations, imaging examination, diagnosis and prognosis of 159 cases were analyzed. Results ①In 159 cases, male patients were in the majority, male and female ratio was about 2:1. Symptom with fever (68.55%), liver discomfort (43.40%), loss of appetite and fatigue (40.88%) were the main performance. ②Results of laboratory examination: erythrocyte sedimentation rate increased (71.76%), abnormal liver function (58.49%), and lower hemoglobin (52.83%). ③The comparation of imaging diagnosis: the positive rates of CT and B-ultrasound were no significant difference (P＞0.05), there existed significantly difference between MRI, B-ultrasound and CT, MRI had a higher positive rate (P＜0.05). ④The preoperative diagnosis rate of hepatic tuberculosis about 13.84%, was low. The misdiagnosis rate was high, during which liver cancer were the most common misdiagnosed. Diagnosis mainly depends on pathological examination. ⑤Medical treatment was the main treatment, and it’s effect was good. Conclusions Hepatic tuberculosis lacked specific clinical manifestations, and the imaging features of various, the diagnostic rate of hepatic tuberculosis was low, and the misdiagnosis rate was high. In order to definite it, histopathological examination is necessary. The first choice of treatment is drug therapy, which is good.