The First Affiliated Hospital of Zhengzhou University has explored the feasibility of day surgery based on the two-way referral system, that is, the patients underwent necessary preoperative preparations and examinations in the county hospital, contacted the referral hospital for referral-related matters, and made an appointment for surgery. After receiving day surgery at the First Affiliated Hospital of Zhengzhou University, the patients underwent short-term observation and treatment in the hospital. When the patients meet the discharge or transfer criteria, they will be discharged or transferred back to primary hospitals for rehabilitation treatment, and the day surgery center will continue to track and guide follow-up diagnosis and treatment. This article introduces the exploration and practice of day surgery for county hospitals in the First Affiliated Hospital of Zhengzhou University. This day surgery mode is highly maneuverable and is of great significance to promote the development of medical services in hospitals at all levels.