The full process information management of daytime surgery can help medical staff complete centralized patient management, improve the closed-loop quality of daytime surgery, and maximize the efficiency and management level of hospital daytime surgery operation. Since 2021, the First Hospital of Lanzhou University has integrated internal information exchange resources, big data, and artificial intelligence, created a full process management platform for daytime surgery, and explored the intelligent management of daytime surgery processes. This article shares the experience of building an intelligent daytime surgery full process management model based on interactive design information system from the aspects of platform interaction design, intelligent management mode, application effectiveness, in order to provide a reference for optimizing intelligent closed-loop management of daytime surgery.