Males typically have high rates of morbidity of primary bladder neck obstruction, while the existing urodynamic examination is invasive and more likely to cause false diagnosis. To build a non-invasive biomechanical detecting system for the male lower urinary tract, a finite element model for male lower urinary tract based on the collodion slice images of normal male lower urinary tract was constructed, and the fluid-structure interaction of the lower urinary tract was simulated based on the real urination environment. The finite element model of the lower urinary tract was validated by comparing the clinical experiment data with the simulation result. The stress, flow rate and deformation of the lower urinary tract were analyzed, and the results showed that the Von Mises stress and the wall shear stress at the membrane sphincter in the normal male lower urinary tract model reached a peak, and there was nearly 1 s delay than in the bladder pressure, which helped to validate the model. This paper lays a foundation for further research on the urodynamic response mechanism of the bladder pressure and flow rate of the lower urinary tract obstruction model, which can provide a theoretical basis for the research of non-invasive biomechanical detecting system.
For those patients with refractory lower urinary tract dysfunction who are not well treated by traditional therapy such as behavior therapy and drug therapy, neuromodulation technologies have gradually become alternative treatments. Several neuromodulation technologies are also used in animal experimental and clinical scientific research by more and more scholars, in order to find more effective methods and mechanisms of treatment of lower urinary tract dysfunction. This article introduces the principle and advantages of common neuromodulation technologies, which focuses on the application in lower urinary tract dysfunction treatment, and analyzes the direction and the broad prospect of neuromodulation.
The management of neurogenic lower urinary tract dysfunction due to spinal cord injury is one of the most challenging tasks in rehabilitation. Considerable progress has been made in the management of lower urinary tract dysfunction in patients with spinal cord injury over the past few decades. However, urinary complications remain one of the most serious complications in patients with spinal cord injury. Lower urinary tract dysfunction in patients with spinal cord injury present with a variety of symptoms and signs that require comprehensive evaluation. The management of lower urinary tract dysfunction in patients with spinal cord injury require tailored and individualized treatment approaches. Based on the clinical practice of rehabilitation at home and abroad, this paper expounds the progress of the assessment and rehabilitation of lower urinary tract dysfunction after spinal cord injury, and puts forward some suggestions for the reference of clinical staff.