Atrial fibrillation is a common clinical arrhythmia with a high incidence. The main clinical treatment methods for atrial fibrillation at present include radiofrequency catheter ablation and cryoablation. In recent years, pulsed field ablation, a new energy source with tissue specificity, is gradually being used in clinical practice. This article presents the world's first case of atrial fibrillation treated with pulsed field surgical ablation, in which the patient underwent surgical intervention of the valves and coronary arteries at the same time and recovered to sinus rhythm intraoperatively. 24 hour-Holter electrocardiogram after 1 month and 3 months showed no atrial fibrillation. The patient’s symptoms, cardiac function, and quality of life improved significantly.