Give full play to the clinical application value of confocal scanning laser ophthalmoscope imaging to improve the diagnosis of ocular fundus diseases_Chinese Journal of Ocular Fundus Diseases

Authors：

 Wei Wenbin , Shao Lei

Beijing Tongren Eye Center, Beijing Key Laboratory of Intraocular Tumor Diagnosis and Treatment, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Medical Artificial Intelligence Research and Verification Key Laboratory of the Ministry of Industry and Information Technology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China;

Corresponding author：

Wei Wenbin, Email: tr_weiwenbin@163.com

Keywords：

Microscopy, confocal; Retinal diseases/diagnosis; Editorial

DOI：

10.3760/cma.j.cn511434-20200414-00160

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Confocal scanning laser ophthalmoscope imaging superimpose two or three kinds of lasers to obtain images of different layers of retina, and then synthesize a pseudo-color fundus image by computer. Confocal scanning laser ophthalmoscope is widely used in outpatient fundus pre-examination and epidemiological screening of large samples due to its features of non-mydriatic, fast imaging, simple operation and high degree of patient cooperation. It has good clinical and scientific application value in the diagnosis and treatment of a variety of fundus diseases. Because of there is still a lack of unified standards for laser fundus photos in China, it is necessary to correctly identify the common fundus lesions in confocal scanning laser ophthalmoscope and to summarize and popularize the method of reading the photos in layers. In addition, we should give full play to the its advantage of layering and locating, and reasonably choose the combination of OCT, OCT angiography, FFA, ICGA, ultrasonography, so as to maximize its clinical application value and help clinical diagnosis.

Citation： Wei Wenbin, Shao Lei. Give full play to the clinical application value of confocal scanning laser ophthalmoscope imaging to improve the diagnosis of ocular fundus diseases. Chinese Journal of Ocular Fundus Diseases, 2020, 36(5): 333-336. doi: 10.3760/cma.j.cn511434-20200414-00160 Copy

1.	Webb RH, Hughes GW, Delori FC. Confocal scanning laser ophthalmoscope[J]. Appl Opt, 1987, 26(8): 1492-1499. DOI: 10.1364/AO.26.001492.
2.	Sharp PF, Manivannan A. The scanning laser ophthalmoscope[J]. Phys Med Biol, 1997, 42(5): 951-966. DOI: 10.1088/0031-9155/42/5/014.
3.	Tan AC, Fleckenstein M, Schmitz-Valckenberg S, et al. Clinical application of multicolor imaging technology[J]. Ophthalmologica, 2016, 236(1): 8-18. DOI: 10.1159/000446857.
4.	Ghoghari H, Rizvi SF, Razzak K, et al. Clinical application of multicolor optical coherence tomography in the diagnosis of retinal pathologies[J]. Pak J Med Sci, 2018, 34(6): 1555-1559. DOI: 10.12669/pjms.346.16388.
5.	Armenti ST, Greenberg JP, Smith RT. Quantitative fundus autofluorescence for the evaluation of retinal diseases[J/OL]. J Vis Exp, 2016(109): 53577[2016-03-11]. http://europepmc.org/article/MED/27023389. DOI:10.3791/53577.
6.	Joung JY, Lee WJ, Lee BR. Comparison of blue and green confocal scanning laser ophthalmoscope imaging to detect retinal nerve fiber layer defects[J]. Korean J Ophthalmol, 2019, 33(2): 131-137. DOI: 10.3341/kjo.2018.0075.
7.	Kromer R, Shafin R, Boelefahr S, et al. An Automated approach for localizing retinal blood vessels in confocal scanning laser ophthalmoscopy fundus images[J]. J Med Biol Eng, 2016, 36(4): 485-494. DOI: 10.1007/s40846-016-0152-x.
8.	Nittala MG, Hariri A, Wong WT, et al. Image scaling difference between a confocal scanning laser ophthalmoscope and a flash fundus camera[J]. Ophthalmic Surg Lasers Imaging Retina, 2015, 46(8): 872-879. DOI: 10.3928/23258160-20150909-13.
9.	Etten PG, Brouwere DD, Westers P, et al. Zero dilation ophthalmoscopy[J]. J Ophthalmic Photogr, 2014, 36: 55-62.
10.	霍妍佼, 杨丽红, 崔蕊, 等. 共焦激光扫描检眼镜与眼底彩色照相对视网膜和脉络膜病变的检出比较[J]. 中华眼底病杂志, 2016, 32(3): 270-274. DOI: 10.3760/cma.j.issn.1005-1015.2016.03.010.Huo YJ, Yang LH, Cui R, et al. Comparison of confocal scanning laser ophthalmoscope and color fundus camera to assess retinal and choroidal disease using[J]. Chin J Ocul Fundus Dis, 2016, 32(3): 270-274. DOI: 10.3760/cma.j.issn.1005-1015.2016.03.010.
11.	Pfau M, Goerdt L, Schmitz-Valckenberg S, et al. Green-light autofluorescence versus combined blue-light autofluorescence and near-infrared reflectance imaging in geographic atrophy secondary to age-related macular degeneration[J]. Invest Ophthalmol Vis Sci, 2017, 58(6): 121-130. DOI: 10.1167/iovs.17-21764.
12.	Feng HL, Sharma S, Stinnett S, et al. Characterization of artifacts associated with multicolor confocal scanning laser ophthalmoscopy[J]. Ophthalmic Surg Lasers Imaging Retina, 2017, 48(10): 810-815. DOI: 10.3928/23258160-20170928-05.
13.	Dai Y, Zhou H, Chu Z, et al. Microvascular changes in the choriocapillaris of diabetic patients without retinopathyinvestigated by swept-source OCT angiograph[J]. Invest Ophthalmol Vis Sci, 2020, 61(3): 50. DOI: 10.1167/iovs.61.3.50.

1. Webb RH, Hughes GW, Delori FC. Confocal scanning laser ophthalmoscope[J]. Appl Opt, 1987, 26(8): 1492-1499. DOI: 10.1364/AO.26.001492.
2. Sharp PF, Manivannan A. The scanning laser ophthalmoscope[J]. Phys Med Biol, 1997, 42(5): 951-966. DOI: 10.1088/0031-9155/42/5/014.
3. Tan AC, Fleckenstein M, Schmitz-Valckenberg S, et al. Clinical application of multicolor imaging technology[J]. Ophthalmologica, 2016, 236(1): 8-18. DOI: 10.1159/000446857.
4. Ghoghari H, Rizvi SF, Razzak K, et al. Clinical application of multicolor optical coherence tomography in the diagnosis of retinal pathologies[J]. Pak J Med Sci, 2018, 34(6): 1555-1559. DOI: 10.12669/pjms.346.16388.
5. Armenti ST, Greenberg JP, Smith RT. Quantitative fundus autofluorescence for the evaluation of retinal diseases[J/OL]. J Vis Exp, 2016(109): 53577[2016-03-11]. http://europepmc.org/article/MED/27023389. DOI:10.3791/53577.
6. Joung JY, Lee WJ, Lee BR. Comparison of blue and green confocal scanning laser ophthalmoscope imaging to detect retinal nerve fiber layer defects[J]. Korean J Ophthalmol, 2019, 33(2): 131-137. DOI: 10.3341/kjo.2018.0075.
7. Kromer R, Shafin R, Boelefahr S, et al. An Automated approach for localizing retinal blood vessels in confocal scanning laser ophthalmoscopy fundus images[J]. J Med Biol Eng, 2016, 36(4): 485-494. DOI: 10.1007/s40846-016-0152-x.
8. Nittala MG, Hariri A, Wong WT, et al. Image scaling difference between a confocal scanning laser ophthalmoscope and a flash fundus camera[J]. Ophthalmic Surg Lasers Imaging Retina, 2015, 46(8): 872-879. DOI: 10.3928/23258160-20150909-13.
9. Etten PG, Brouwere DD, Westers P, et al. Zero dilation ophthalmoscopy[J]. J Ophthalmic Photogr, 2014, 36: 55-62.
10. 霍妍佼, 杨丽红, 崔蕊, 等. 共焦激光扫描检眼镜与眼底彩色照相对视网膜和脉络膜病变的检出比较[J]. 中华眼底病杂志, 2016, 32(3): 270-274. DOI: 10.3760/cma.j.issn.1005-1015.2016.03.010.Huo YJ, Yang LH, Cui R, et al. Comparison of confocal scanning laser ophthalmoscope and color fundus camera to assess retinal and choroidal disease using[J]. Chin J Ocul Fundus Dis, 2016, 32(3): 270-274. DOI: 10.3760/cma.j.issn.1005-1015.2016.03.010.
11. Pfau M, Goerdt L, Schmitz-Valckenberg S, et al. Green-light autofluorescence versus combined blue-light autofluorescence and near-infrared reflectance imaging in geographic atrophy secondary to age-related macular degeneration[J]. Invest Ophthalmol Vis Sci, 2017, 58(6): 121-130. DOI: 10.1167/iovs.17-21764.
12. Feng HL, Sharma S, Stinnett S, et al. Characterization of artifacts associated with multicolor confocal scanning laser ophthalmoscopy[J]. Ophthalmic Surg Lasers Imaging Retina, 2017, 48(10): 810-815. DOI: 10.3928/23258160-20170928-05.
13. Dai Y, Zhou H, Chu Z, et al. Microvascular changes in the choriocapillaris of diabetic patients without retinopathyinvestigated by swept-source OCT angiograph[J]. Invest Ophthalmol Vis Sci, 2020, 61(3): 50. DOI: 10.1167/iovs.61.3.50.

Next Article
Optical coherence tomography angiography features of angioid streaks

Chinese Journal of Ocular Fundus Diseases

Give full play to the clinical application value of confocal scanning laser ophthalmoscope imaging to improve the diagnosis of ocular fundus diseases

Abstract Full text Figures/Tables Video References Cited by

Next Article

Format

Content