Optical coherence tomography imaging features of peripheral retinal abnormalities in high myopia_Chinese Journal of Ocular Fundus Diseases

Authors：

Wu Pengwei , Liu Hui , Wu Yingjie , Jiang Yongqiang ,  Guo Xiaohong

Henan Provincial People' Hospital, Henan Eye Hospital, Henan Eye Institute, People's Hospital of Zhengzhou University, Zhengzhou 450003, China;

Corresponding author：

Guo Xiaohong, Email: gxh2022@163.com

Keywords：

Myopia, degenerative; Retinoschisis; Retinal perforations; Tomography, optical coherence

DOI：

10.3760/cma.j.cn511434-20220110-00023

Video：

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Objective To observe the imaging features of optical coherence tomography (OCT) in peripheral retinal abnormalities of high myopia (HM). Methods A retrospective series of case studies were conducted. From March 2019 to March 2021, 38 cases (50 eyes) in high myopia with peripheral retinal abnormalities who were confirmed to Henan Eye Hospital were enrolled in the study. There were 21 eyes in 17 males and 29 eyes in 21 females, age was 39.58±15.29 years, diopter was (－9.10±2.44) D. All patients underwent wide-angle fundus photography and OCT examination. According to wide-angle fundus photography and OCT, HM with peripheral retinal abnormalities were classified into white-without-pressure, black-without-pressure, lattice degeneration, peripheral pigmented degeneration, retinoschisis and retinal holes. OCT imaging features of peripheral abnormalities in high myopia was observed. Results In 50 eyes, 65 peripheral retinal abnormalities were observed by OCT. In 6 white-without-pressure, intense hyperreflectivity was shown at the level of the ellipsoid zone that abruptly transitions to relative hyporeflectivity at the dark border of the lesion. In 16 black-without-pressure, reflectivity of the ellipsoid zone decreased. In 10 sites of lattice degeneration, cystoid degeneration, local thinning, retinal tear at the posterior edge and boundary of the lesion was shown, whcih may be accompanied by local vitreous condensation and traction. In 4 peripheral pigmented degeneration, retinal interlayer hyperreflectivity was shown. In 12 retinoschisis, neuroepith-elial separation was connected by vertical bridge or columnar light bands, of which 3 were accompanied with localized retinal detachment and 2 with splitting-related retinal vascular abnormalities. In 17 retinal holes, full layer of neuroepithelium lost, that 12 zones were accompanied with retinal detachment with vitreous adhesion or traction. Conclusion OCT manifestations of peripheral retinal abnormalities in HM varies.

Citation： Wu Pengwei, Liu Hui, Wu Yingjie, Jiang Yongqiang, Guo Xiaohong. Optical coherence tomography imaging features of peripheral retinal abnormalities in high myopia. Chinese Journal of Ocular Fundus Diseases, 2022, 38(6): 478-483. doi: 10.3760/cma.j.cn511434-20220110-00023 Copy

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11.	Tsai CY, Hung KC, Wang SW, et al. Spectral-domain optical coherence tomography of peripheral lattice degeneration of myopic eyes before and after laser photocoagulation[J]. J Formos Med Assoc, 2019, 118(3): 679-685. DOI: 10.1016/j.jfma.2018.08.005.
12.	Sborgia G, Boscia F, Niro A, et al. Morphologic and functional outcomes of different optical coherence tomography patterns of myopic foveoschisis after vitrectomy and inner limiting membrane peeling[J]. Eye (Lond), 2019, 33(11): 1768-1775. DOI: 10.1038/s41433-019-0490-3.
13.	Song M, Shen M, Zhou Y, et al. Observation of vitreous features using enhanced vitrrous imaging otpical coherence tomography in highly myopic retinoschisis[J]. Retina, 2019, 39(9): 1732-1741. DOI: 10.1097/IAE.0000000000002226.
14.	Frisina R, Gius I, Palmieri M, et al. Myopic traction maculopathy: diagnostic and management strategies[J]. Clin Ophthalmol, 2020, 14: 3699-3708. DOI: 10.2147/OPTH.S237483.
15.	Guo XX, Chen X, Li SS, et al. Measurements of the parapapillary atrophy area and other fundus morphological features in high myopia with or without posterior staphyloma and myopic traction maculopathy[J]. Int J Ophthalmol, 2020, 13(8): 1272-1280. DOI: 10.18240/ijo.2020.08.14.
16.	Rao P, Dedania VS, Drenser KA. Congenital X-linked retinoschisis: an updated clinical review[J]. Asia Pac J Ophthalmol (Phila), 2018, 7(3): 169-175. DOI: 10.22608/APO.201803.
17.	Luo M, Du H, Ding H, et al. Peripheral retinal neovascularization secondary to highly myopic superficial retinoschisis: a case report[J]. BMC Ophthalmol, 2020, 20(1): 25. DOI: 10.1186/s12886-020-1308-6.
18.	Wilkinson CP. Interventions for asymptomatic retinal breaks and lattice degeneration for preventing retinal detachment[J/OL]. Cochrane Database Syst Rev, 2014(9): D3170[2014-09-05]. https://pubmed.ncbi.nlm.nih.gov/25191970/. DOI: 10.1002/14651858.CD003170.pub4.

1. Huang D, Swanson EA, Lin CP, et al. Optical coherence tomography[J]. Science, 1991, 254(5035): 1178-1181. DOI: 10.1126/science.1957169.
2. Uji A, Yoshimura N. Application of extended field imaging to optical coherence tomography[J]. Ophthalmology, 2015, 122(6): 1272-1274. DOI: 10.1016/j.ophtha.2014.12.035.
3. Reznicek L, Klein T, Wieser W, et al. Megahertz ultra-wide-field swept-source retina optical coherence tomography compared to current existing imaging devices[J]. Graefe's Arch Clin Exp Ophthalmol, 2014, 252(6): 1009-1016. DOI: 10.1007/s00417-014-2640-4.
4. Choudhry N, Golding J, Manry MW, et al. Ultra-widefield steering-based spectral-domain optical coherence tomography imaging of the retinal periphery[J]. Ophthalmology, 2016, 123(6): 1368-1374. DOI: 10.1016/j.ophtha.2016.01.045.
5. Spaide RF, Michael E. Peripheral retinal abnormalities[M]//Spaide RF, Ohno-Matsi K, Yannuuz LA. Pathologic myopia. New York: Springer Nature, 2014: 255-271.
6. 郭彤. 激光治疗视网膜周边变性和裂孔[M]//张惠蓉. 眼底病激光治疗. 北京: 人民卫生出版社, 2012: 142-146.Guo T. Laser treatment of peripheral retinal degeneration and retinal holes[M]//Zhang HR. Laser treatment of fundus diseases. Beijing: People's Medical Publishing House, 2012: 142-146.
7. Freeman HM. Fellow eyes of giant retinal breaks[J]. Mod Probl Ophthalmol, 1979, 20: 267-274.
8. Nagpal KC, Goldberg MF, Asdourian G, et al. Dark-without-pressure fundus lesions[J]. Br J Ophthalmol, 1975, 59(9): 476-479. DOI: 10.1136/bjo.59.9.476.
9. Fawzi AA, Nielsen JS, Mateo-Montoya A, et al. Multimodal imaging of white and dark without pressure fundus lesions[J]. Retina, 2014, 34(12): 2376-2387. DOI: 10.1097/IAE.0000000000000388.
10. Flaxel CJ, Adelman RA, Bailey ST, et al. Posterior vitreous detachment, retinal breaks, and lattice degeneration preferred practice pattern®[J]. Ophthalmology, 2020, 127(1): P146-P181. DOI: 10.1016/j.ophtha.2019.09.027.
11. Tsai CY, Hung KC, Wang SW, et al. Spectral-domain optical coherence tomography of peripheral lattice degeneration of myopic eyes before and after laser photocoagulation[J]. J Formos Med Assoc, 2019, 118(3): 679-685. DOI: 10.1016/j.jfma.2018.08.005.
12. Sborgia G, Boscia F, Niro A, et al. Morphologic and functional outcomes of different optical coherence tomography patterns of myopic foveoschisis after vitrectomy and inner limiting membrane peeling[J]. Eye (Lond), 2019, 33(11): 1768-1775. DOI: 10.1038/s41433-019-0490-3.
13. Song M, Shen M, Zhou Y, et al. Observation of vitreous features using enhanced vitrrous imaging otpical coherence tomography in highly myopic retinoschisis[J]. Retina, 2019, 39(9): 1732-1741. DOI: 10.1097/IAE.0000000000002226.
14. Frisina R, Gius I, Palmieri M, et al. Myopic traction maculopathy: diagnostic and management strategies[J]. Clin Ophthalmol, 2020, 14: 3699-3708. DOI: 10.2147/OPTH.S237483.
15. Guo XX, Chen X, Li SS, et al. Measurements of the parapapillary atrophy area and other fundus morphological features in high myopia with or without posterior staphyloma and myopic traction maculopathy[J]. Int J Ophthalmol, 2020, 13(8): 1272-1280. DOI: 10.18240/ijo.2020.08.14.
16. Rao P, Dedania VS, Drenser KA. Congenital X-linked retinoschisis: an updated clinical review[J]. Asia Pac J Ophthalmol (Phila), 2018, 7(3): 169-175. DOI: 10.22608/APO.201803.
17. Luo M, Du H, Ding H, et al. Peripheral retinal neovascularization secondary to highly myopic superficial retinoschisis: a case report[J]. BMC Ophthalmol, 2020, 20(1): 25. DOI: 10.1186/s12886-020-1308-6.
18. Wilkinson CP. Interventions for asymptomatic retinal breaks and lattice degeneration for preventing retinal detachment[J/OL]. Cochrane Database Syst Rev, 2014(9): D3170[2014-09-05]. https://pubmed.ncbi.nlm.nih.gov/25191970/. DOI: 10.1002/14651858.CD003170.pub4.

Chinese Journal of Ocular Fundus Diseases

Optical coherence tomography imaging features of peripheral retinal abnormalities in high myopia

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