Zong Yuan 1,2 , Zhang Ting 1,2 , Zhuang Hong 1,2 , Gao Fengjuan 1,2 , Jiang Rui 1,2 , Huang Xin 1,2
  • 1. Department of Ophthalmology, The Eye-ENT Hospital of Fudan University, Shanghai 200031, China;
  • 2. Ministry of Health Key Laboratory of Myopia, Shanghai Key Laboratory of Visual Damage and Reconstruction, Shanghai 200031, China;
  • Zong Yuan and Zhang Ting are contributed equally to the article;
Huang Xin, Email: huangxin2007@aliyun.com
Endophthalmitis; Corneal ulcer; Sutures; Anti-infective agents; Vitrectomy
10.3760/cma.j.cn511434-20220307-00121
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Objective To observe the clinical features and prognosis of eyes with corneal suture-related infective endophthalmitis. Methods A retrospective interventional case series. From January 2020 to December 2021, 5 patients (5 eyes) with corneal suture-related infectious endophthalmitis diagnosed by ophthalmic examination at Department of Ophthalmology of the Eye-ENT Hospital of Fudan University were included in the study. Among them, there were 3 males and 2 females; all had unilateral disease; the mean age was 30.80±21.98 years. Sutures of 4 cases were secondary to lens related surgery and of 1 case was secondary to penetrating keratoplasty. Average retention time of corneal suture was 20.00±7.41 months. Of the 5 eyes, corneal sutures were removed in 1 eye due to redness and eye pain in another hospital; 3 eyes were loosened of the sutures in the remaining 4 eyes. The patients were given standard treatment for infectious endophthalmitis, including systemic and local anti-infective therapy; corneal suture removal, intraocular injection, and vitrectomy (PPV). In PPV, it was decided whether to give silicone oil filling according to the situation. The follow-up time after treatment was 11.00±7.38 months. The best corrected visual acuity (BCVA), B-mode ultrasound and microbial culture results of the affected eye before and after surgery were observed and analyzed.Results Infiltrates, ulcers, or abscesses surrounding the suture may be seen on the cornea of the affected eye. B-mode ultrasonography showed vitreous opacity, preretinal cords, and spherical wall edema in the entire segment of the affected eye. The results of vitreous humor culture were positive in 3 eyes, which were Streptococcus viridis, Staphylococcus hominis subspecies, Staphylococcus epidermidis. After treatment, all the intraocular infections in the affected eyes were successfully controlled, and there were no cases of enucleation of ocular contents or enucleation. Before treatment, the BCVA of the affected eye was from no light perception to counting fingers; after treatment, 2 eyes had BCVA＞0.3. Conclusions Infiltration, ulcers or abscesses around the sutures can be seen in the cornea of corneal suture-related infective endophthalmitis patients, which are related to the long-term retention of the sutures in the eye. Most of the affected eyes have loose sutures when they go to the doctor; timely treatment can effectively control the infection, and some eyes have good visual prognosis.

Citation： Zong Yuan, Zhang Ting, Zhuang Hong, Gao Fengjuan, Jiang Rui, Huang Xin. Five cases of corneal suture-associated infectious endophthalmitis. Chinese Journal of Ocular Fundus Diseases, 2022, 38(5): 366-370. doi: 10.3760/cma.j.cn511434-20220307-00121 Copy

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