Research progress on the correlation between bronchopulmonary dysplasia and retinopathy of prematurity_Chinese Journal of Ocular Fundus Diseases

Authors：

Zhang Caiyu ,  Sun Huiqing

Department of Neonatal Medicine, Children's Hospital Affiliated of Zhengzhou University, Zhengzhou 450018, China;

Corresponding author：

Sun Huiqing, Email: s_huiqing@sina.com

Keywords：

Bronchopulmonary dysplasia; Retinopathy of prematurity; Angiogenesis; Premature infants; Review

DOI：

10.3760/cma.j.cn511434-20240925-00357

Video：

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Abstract Full text Figures/Tables Video References Cited by

Bronchopulmonary dysplasia (BPD) and retinopathy of prematurity (ROP) are common and critically important diseases of preterm infants. The common feature of both conditions is altered angiogenesis and pathological changes in the case of incomplete organ development. The interaction of multiple factors leads to abnormal angiogenesis, which not only increases the possibility of comorbidity of BPO and ROP, but also reveals the potential co-pathogenesis between the two. However, the specific mechanism of this angiogenic balance in the occurrence and development of BPD or ROP is still unclear, and there are no animal models to explore the pathogenesis of both diseases. At present, effective prevention measures for BPO and ROP are still lacking, and treatment methods mainly rely on drug therapy and surgery. In the future, more studies should be conducted to find common therapeutic targets for factors affecting angiogenesis, so as to provide better treatment options for BPD and ROP and improve the effectiveness of treatment.

Citation： Zhang Caiyu, Sun Huiqing. Research progress on the correlation between bronchopulmonary dysplasia and retinopathy of prematurity. Chinese Journal of Ocular Fundus Diseases, 2025, 41(2): 163-168. doi: 10.3760/cma.j.cn511434-20240925-00357 Copy

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Chinese Journal of Ocular Fundus Diseases

Research progress on the correlation between bronchopulmonary dysplasia and retinopathy of prematurity

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